Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1.
宿主种属
兔(Rabbit)
特异性
CCL25
种属反应性
人(Human),小鼠(Mouse)
免疫原
A synthetic peptide derived from human CCL25 (AA 30-110)