7 transmembrane protein with no EGF like N terminal domains 1 antibody | BFPP antibody | DKFZp781L1398 antibody | EGF TM7 like antibody | G protein coupled receptor 56 antibody | G-protein coupled receptor 56 antibody | GPR 56 antibody | Gpr56 antibody |
规格或纯度
ExactAb™, 无载体, 已验证, 见COA
生化机理
Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, PubMed:21724588). Plays an essential role in testis development (By similarity). ADGRG1 N-terminal fragment. Plays a critical role in cancer progression by activating VEGFA production and angiogenesis through a signaling pathway mediated by PRKCA (PubMed:21724588).
宿主种属
小鼠(Mouse)
特异性
GPR56
种属反应性
人(Human)
免疫原
Recombinant protein of Human GPR56.
阳性对照
WB: A431 cell lysates.
偶联
Unconjugated
备注
备注：此产品可替代 Ab106255
克隆类型
单克隆抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein G purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBS, 0.09% Sodium azide, pH 7.4
防腐剂
0.09% Sodium azide
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。
图片
GPR56 Mouse mAb (Ab106254) - Western Blot
All lanes: GPR56 Mouse mAb (Ab106254) at 1/500 dilution
Samples: Lysates at 30 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/5000 dilution
ZJ25F1129876
危险品化学品经营许可证（带存储）