Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
宿主种属
大鼠(Rat)
特异性
Histone H2A
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human Histone H2A (AA 70-100).
阳性对照
WB: Rat lung, HeLa, Hep G2, MCF7, A549, K562 and NIH/3T3 lysates. IHC: Human colon tissue. IF/ICC: HeLa cells.
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Histone H2A Antibody (Ab107643) - Western Blot All lanes: Recombinant Histone H2A Antibody (Ab107643) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 15 kDa Exposure time: 100.0 s
Recombinant Histone H2A Antibody (Ab107643) - IF/ICC Immunofluorescent analysis of HeLa cells, using Recombinant Histone H2A Antibody (Ab107643).
Recombinant Histone H2A Antibody (Ab107643) - IHC Immunohistochemical analysis of paraffin-embedded human colon, using Recombinant Histone H2A Antibody (Ab107643).
ZJ25F0420708
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