Contributes to the stabilization of the junctional membrane complexes, which are common to excitable cells and mediate cross-talk between cell surface and intracellular ion channels. Probably acts by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum. Contributes to the construction of skeletal muscle triad junctions, and plays an essential role in heart development.
宿主种属
小鼠(Mouse)
特异性
JPH2
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
Recombinant full length protein of human JPH2 produced in HKE293T cell.
阳性对照
WB: HepG2, HeLa, SYT2, A549, COS7, Jurkat and MDCK lysates.