Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
宿主种属
兔(Rabbit)
特异性
MBL2
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human MBL2
表位
The epitope is on the head-neck region of the MBL protein chain.
阳性对照
WB: Mouse pancreas lysate. IHC: Human tonsil tissue