计算溶液所需的质量、体积或浓度。
| 活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
|---|
PARN Mouse mAb
有货
为什么选择此级别
，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
概述
Mouse anti Human PARN Antibody, Monoclonal (OTI1G5), could be used for WB, IHC and so on.
Application:
WB: 1/2000
IHC: 1/150
规格
产品名称
PARN Mouse mAb
别名
多聚腺苷酸特异性核糖核酸抗体 | 多聚腺苷酸特异性核糖核酸单克隆抗体 | PARN抗体 | PARN单克隆抗体
英文别名
DAN antibody | Deadenylating nuclease antibody | Deadenylation nuclease antibody | PARN antibody | PARN_HUMAN antibody | Poly A specific ribonuclease antibody | Poly(A) specific ribonuclease antibody | Poly(A)-specific ribonuclease PARN antibody | Polyade
规格或纯度
见 COA
生化机理
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. Interacts with both the 3'-end poly(A) tail and the 5'-end cap structure during degradation, the interaction with the cap structure being required for an efficient degradation of poly(A) tails. Involved in nonsense-mediated mRNA decay, a critical process of selective degradation of mRNAs that contain premature stop codons. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly via its interaction with KHSRP. Probably mediates the removal of poly(A) tails of AREs mRNAs, which constitutes the first step of destabilization.
宿主种属
小鼠(Mouse)
特异性
PARN
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
Recombinant protein of human PARN (AA 1-266).
阳性对照
WB: HT29 lysates. IHC: Human ovary, lymph node, lymphoma, tonsil tissue.
偶联
Unconjugated
克隆类型
单克隆抗体
Format
Whole IgG
纯化方法
Protein A/G purified
浓度
见 COA
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3
防腐剂
0.02% Sodium azide
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃（1-2周）；长期储存-20℃（12个月）；收货后建议分装，避免反复冻融。
应用
应用名称
稀释比例
WB
1/2000
IHC
1/150
技术文档
高级数据
关联靶点（人）
PARN
Tbio
聚腺苷酸特异性核糖核酸酶 PARN(Poly(A)-specific ribonuclease PARN)
(0 活性数据)
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
溶液计算器
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