Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
宿主种属
小鼠(Mouse)
特异性
PD-L1
种属反应性
人(Human)
免疫原
Full length Human PD-L1.
阳性对照
IHC-P: Human NSCLC tissue; PD L1 transfected HEK-293 cells. Human lung carcinoma and placenta tissue. mIHC: Human tonsil tissue. WB: CHO-PD-L1 (PD-L1 stably expressed Chinese hamster ovary epithelial cell) whole cell lysate. A549 treated with 100ng/ml IFN
偶联
Unconjugated
备注
备注：此产品可替代 Ab121011
克隆类型
单克隆抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein G purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBS, pH 7.0
储存条件
2-8°C储存,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
Store at 2-8℃ long term (12 months). Do not freeze.
图片
PD-L1 Mouse mAb (Ab121019) - Flow Cytometry
Flow Cytometry analysis of MDA-MB-231 cells labelling PD-L1 (red) with PD-L1 Mouse mAb (Ab121019) at 0.2 μg/mL for 1 hour at 4°C and detected with AF488 - conjugated affinipure goat anti - Mouse IgG. Blue - Mouse IgG Isotype Control Antibody (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
ZJ26F0131686
危险品化学品经营许可证（带存储）