Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
宿主种属
大鼠(Rat)
特异性
PD-L1
种属反应性
小鼠(Mouse)
免疫原
Mouse CD274 protein.
偶联
Unconjugated
备注
此产品可替代 Ab121006
克隆类型
单克隆抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A or G purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBS, pH 7.2
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at 2-8℃ short term (2 months). Store at -20℃ or -80°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
PD-L1 Rat mAb (Ab121024) - Flow Cytometry
Flow Cytometry analysis of C57BL/6 mouse splenocytes cells labelling PD-L1 with PD-L1 Rat mAb (Ab121024) (right panel) at 0.2 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Ab141774) (left panel) and detected with AF 647 - conjugated affinipure goat anti - Rat IgG.
PD-L1 Rat mAb (Ab121024) - Flow Cytometry
Flow Cytometry analysis of C57BL/6 mouse splenocytes cells labelling PD-L1 (red) with PD-L1 Rat mAb (Ab121024) at 0.2 μg/mL for 1 hour at 4°C and detected with AF 647 - conjugated affinipure goat anti - Rat IgG. Blue - Rat IgG Isotype Control Antibody (Ab141774). Black - Unlabelled control, cells without incubation with primary antibody.