Rabbit anti Human TRPV6 Antibody, Polyclonal antibody, could be used for WB, IHC and so on.
规格
产品名称
TRPV6 Antibody
别名
钙转运蛋白1抗体 | 钙转运蛋白1多克隆抗体 | TRPV6抗体 | TRPV6多克隆抗体
英文别名
ABP/ZF antibody | ABPZF antibody | Alu binding protein with zinc finger domainantibody | Calcium channel CaT1 antibody | Calcium transport protein 1 antibody | CaT L antibody | CaT Like antibody | CaT-L antibody | CaT-like antibody | CaT1 antibody | ecac
规格或纯度
见COA
生化机理
Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Post-translational: Glycosylated. Phosphorylation by PRKCA at the calmodulin binding site delays channel inactivation.
宿主种属
兔(Rabbit)
特异性
TRPV6
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human TRPV6.
阳性对照
WB: HeLa, HT-29 lysates. IHC: Human liver cancer tissue.