Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
宿主种属
兔(Rabbit)
特异性
C4BPB
种属反应性
人(Human),小鼠(Mouse)
免疫原
Recombinant protein of human C4 binding protein (AA 18-250).