Gitr | Activation-inducible TNFR family receptor | AITR | AITRTNF receptor superfamily activation-inducible protein | CD357 antigen | CD357 | GITR-D | GITRtumor necrosis factor receptor superfamily member 18 | Glucocorticoid-induced TNFR-related protein |
规格或纯度
ExactAb™, 已验证, 0.5 mg/mL
生化机理
TNFSF18 的受体。似乎参与了活化的 T 淋巴细胞与内皮细胞之间的相互作用,以及对 T 细胞受体介导的细胞死亡的调节。通过 TRAF2/NIK 途径介导 NF-kappa-B 激活。
宿主种属
大鼠(Rat)
特异性
GITR/CD357
种属反应性
小鼠(Mouse)
免疫原
Mouse CD25+ CD4+ T cells
阳性对照
Flow: C57BL/6 mouse splenocytes.
偶联
Biotin
克隆类型
单克隆抗体
克隆号
DTA-1
Format
Whole IgG
亚型
Rat IgG2b
轻链亚型
lambda
纯化方法
Protein G purified
浓度
0.5 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
2-8°C储存,避光,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
未稀释的抗体溶液应保存在 2°C 至 8°C 之间,避免长时间暴露在光线下。切勿冷冻。
图片
GITR/CD357 Rat mAb (Biotin) (Ab190289) - Flow Cytometry Two-color flow cytometric analysis of GITR/CD357 expression on mouse splenocytes. C57BL/6 mouse spleen cells were stained with CD25 Rat mAb (APC) (Ab179012) and either Rat IgG Isotype Control Antibody (Biotin) (Ab180310; Left panel) or GITR/CD357 Rat mAb (Biotin) (Ab190289; Right panel) at 1 μg/mL. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Total viable cells were used for analysis.
应用
应用名称
稀释比例
Flow Cytometry
≤0.3 μg/test,
the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume