Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
宿主种属
小鼠(Mouse)
特异性
CD11b
种属反应性
人(Human)
免疫原
Rheumatoid synovial cells and human monocytes.
阳性对照
Flow Cytometry: Human peripheral blood monocytes
偶联
AF647
Excitation(nm)
Red Laser(633nm)
Emission(nm)
668nm
Ex/Em(nm)
Ex:650nm;Em:668nm
克隆类型
单克隆抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein G purified
浓度
5 μL/test
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
2-8°C储存,避光,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
图片
CD11b Mouse mAb (AF647) (Ab191612) - Flow Cytometry Flow cytometry analysis of CD11b expression by human peripheral blood cells (right panel) compared to an isotype control (left panel). Cells were stained with CD11b Mouse mAb (AF647) (Ab191612) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (AF647) (Ab190077).
CD11b Mouse mAb (AF647) (Ab191612) - Flow Cytometry Flow cytometry analysis of CD11b expression by human peripheral blood monocytes (red) compared to an isotype control (blue). Cells were stained with CD11b Mouse mAb (AF647) (Ab191612) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF647) (Ab190077). Black - Unlabelled control, cells without incubation with primary antibody.
应用
应用名称
稀释比例
Flow Cytometry
5μl/test
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.
ZJ25F0724733
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