SIRP alpha/CD172a Rat mAb (Biotin)

货号: Ab191788
有货
级别和纯度: ExactAb™ ? ExactAb™ —— 阿拉丁强调精准和验证质量的抗体系列。适用于可靠、特异性经验证的抗体应用。 已验证 ? 已验证级 —— 发布前在特定应用中确认性能。当需要试剂按声称工作的书面保证时使用。 0.5 mg/mL
应用
Flow Cytometry
宿主种属
大鼠(Rat)
种属反应性
小鼠(Mouse)
亚型
Rat IgG1
克隆号
P84
偶联
Biotin
★
规格
库存
价格
数量
10μg
Ab191788-10μg
现货 Stock Image
¥374.90
25μg
Ab191788-25μg
现货 Stock Image
¥674.90
100μg
Ab191788-100μg
现货 Stock Image
¥1,499.90
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概述


Rat anti Mouse SIRP alpha/CD172a Antibody, Monoclonal (P84), could be used for in vivo SIRPα blocking, in vitro SIRPα blocking, WB, IP, Flow and so on.

规格

产品名称
SIRP alpha/CD172a Rat mAb (Biotin)
别名
信号调节蛋白α(SIRPa)抗体|SIRP alpha/CD172a抗体|生物素标记的SIRP alpha/CD172a抗体|SIRP alpha/CD172a 大鼠单克隆抗体(生物素)|SIRP alpha/CD172a 大鼠单抗(生物素)
英文别名
Bit|SIRP|SHP-1|Ptpns1|BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs|Brain Ig-like molecule with tyrosine-based activation motifs|CD172 antigen-like family member A|CD172a antigen|CD172a|Inhibitory receptor SHPS-1|Macrophage fusion receptor|MFR|MFRtyrosine phosphatase SHP substrate 1|MyD-1 antigen|MYD1|MYD-1|P84|protein tyrosine phosphatase, non-receptor type substrate 1|SHP substrate 1|SHPS1|SHPS-1|SHPS1CD172A|signal-regulatory protein alpha|Signal-regulatory protein alpha-1|Signal-regulatory protein alpha-2|Signal-regulatory protein alpha-3|SIRP alpha|SIRPA|SIRPalpha|Sirp-alpha-1|SIRPalpha2|Sirp-alpha-2|Sirp-alpha-3|SIRPtyrosine-protein phosphatase non-receptor type substrate 1|Signal regulatory protein alpha type 1 antibody|Bit antibody|Brain Ig like molecule with tyrosine based activation motifs antibody|Brain Ig-like molecule with tyrosine-based activation motifs antibody|Brain immunoglobulin like molecule with tyrosine based activation motifs antibody|CD172 antigen like family member A antibody|CD172 antigen-like family member A antibody|CD172a antibody|CD172a antigen antibody|Inhibitory receptor SHPS-1 antibody|Macrophage fusion receptor antibody|MFR antibody|MYD 1 antibody|Myd 1 antigen antibody|MyD-1 antigen antibody|p84 antibody|Protein tyrosine phosphatase non receptor type substrate 1 antibody|PTPNS1 antibody|SHP substrate 1 antibody|SHPS-1 antibody|SHPS1 antibody|Signal regulatory protein alpha 2 antibody|Signal regulatory protein alpha 3 antibody|Signal regulatory protein alpha antibody|Signal regulatory protein alpha type 2 antibody|Signal-regulatory protein alpha-1 antibody|Signal-regulatory protein alpha-2 antibody|Signal-regulatory protein alpha-3 antibody|SIRP antibody|Sirp-alpha-1 antibody|Sirp-alpha-2 antibody|Sirp-alpha-3 antibody|SIRPA antibody|SIRPalpha antibody|SIRPalpha1 antibody|SIRPalpha2 antibody|SIRPalpha3 antibody|Tyrosine phosphatase SHP substrate 1 antibody|Tyrosine protein phosphatase non receptor type substrate 1 antibody|Tyrosine-protein phosphatase non-receptor type substrate 1 antibody|Biotin anti-mouse CD172a (SIRPα) Antibody|Biotin Rat Anti-Mouse CD172a|CD172a (SIRP alpha) Monoclonal Antibody (P84), Biotin|Biotin Anti-Mouse CD172a/SIRPα Antibody[P84]
规格或纯度
ExactAb™, 已验证, 0.5 mg/mL
生化机理
CD47 的免疫球蛋白样细胞表面受体。作为对接蛋白,诱导 PTPN6、PTPN11 和其他结合伙伴从细胞膜转位到质膜。支持小脑神经元的粘附、神经元突起和胶质细胞的附着。可能在突触发生过程中的细胞内信号传导和突触功能中发挥关键作用(相似)。参与细胞粘附、生长因子或胰岛素诱导的受体酪氨酸激酶偶联细胞反应的负向调节。介导吞噬、肥大细胞活化和树突状细胞活化的负向调节。与 CD47 结合可阻止未成熟树突状细胞的成熟,并抑制成熟树突状细胞产生细胞因子。
宿主种属
大鼠(Rat)
特异性
SIRP alpha/CD172a
种属反应性
小鼠(Mouse)
免疫原
Mouse brain membrane protein
阳性对照
Flow: C57BL/6 mouse bone marrow cells.
偶联
Biotin
克隆类型
单克隆抗体
Format
Whole IgG
亚型
Rat IgG1
轻链亚型
kappa
纯化方法
Protein A purified
浓度
0.5 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
2-8°C储存,避光,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
未稀释的抗体溶液应保存在 2°C 至 8°C 之间,避免长时间暴露在光线下。切勿冷冻。
图片

SIRP alpha/CD172a Rat mAb (Biotin) (Ab191788) - Flow Cytometry
Flow cytometry analysis of SIRP alpha/CD172a expression by C57BL/6 mouse bone marrow cells (right panel) compared to an isotype control (left panel). Cells were stained with SIRP alpha/CD172a Rat mAb (Biotin) (Ab191788) at 0.2μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Left panel - Rat IgG Isotype Control Antibody (Biotin) (Ab180310).

SIRP alpha/CD172a Rat mAb (Biotin) (Ab191788) - Flow Cytometry
Flow cytometry analysis of SIRP alpha/CD172a expression by C57BL/6 mouse bone marrow cells (red) compared to an isotype control (blue). Cells were stained with SIRP alpha/CD172a Rat mAb (Biotin) (Ab191788) at 0.2μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.

应用
应用名称
稀释比例
Flow Cytometry

≤0.3 μg/test, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume

高级数据

关联靶点(人)
SIRPA Tbio 酪氨酸蛋白磷酸酶非受体型底物 1(Tyrosine-protein phosphatase non-receptor type substrate 1) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
质检证书(CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F1012414ZJ24F1012414 分析证书 Ab191788
ZJ24F1012415ZJ24F1012415 分析证书 Ab191788
ZJ24F1012416ZJ24F1012416 分析证书 Ab191788
技术文档和文章
溶液计算器

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