May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.
宿主种属
叙利亚仓鼠(Syrian hamster)
特异性
Podoplanin/gp36
种属反应性
小鼠(Mouse)
免疫原
Mouse tymic epithelial cells
阳性对照
Flow: C2C12 cells
偶联
PE-Cy5
Excitation(nm)
Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm)
Emission(nm)
670nm
Ex/Em(nm)
Ex:565nm;Em:670nm
克隆类型
单克隆抗体
Format
Whole IgG
纯化方法
Protein A purified
浓度
0.5 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
2-8°C储存,避光,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
图片
Podoplanin/gp36 Syrian hamster mAb (PE-Cy5) (Ab211198) - Flow Cytometry Flow cytometry analysis of Podoplanin/gp36 expression by C2C12 cells (red) compared to an isotype control (blue). Cells were stained with Podoplanin/gp36 Syrian hamster mAb (PE-Cy5) (Ab211198) at 0.3μg/test for 1 hour at 4°C. Blue - Syrian hamster lgG-kappa (PE-Cy5), anti-HEL (Ab212183). Black - Unlabelled control, cells without incubation with primary antibody.
应用
应用名称
稀释比例
Flow Cytometry
≤1.0 μg/test. For flow cytometric staining, the suggested use of this reagent is ≤1.0 μg per million cells in 100 µL staining volume.