May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Recombinant protein corresponding to Human Caveolin-1
阳性对照
Flow Cytometry: HeLa cells
偶联
AF555
Excitation(nm)
Green Laser(532nm)
Emission(nm)
568nm
Ex/Em(nm)
Ex:553nm;Em:568nm
克隆类型
单克隆抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
0.5 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 50% glycerol, 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
避光,-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C. Protect from light. Avoid freeze/thaw cycles.
图片
Caveolin-1 Mouse mAb (AF555) (Ab219234) - Flow Cytometry Flow cytometry analysis of Caveolin-1 expression by Hela cells (red) compared to an isotype control (blue). Cells were fixed and permeabilized with 100% methanol and then stained with Caveolin-1 Mouse mAb (AF555) (Ab219234) (red) at 1/150 dilution for 30 minutes at 4°C in the dark. Blue - Mouse IgG (AF555) (Ab190246).
ZJ25F0927388
危险品化学品经营许可证（带存储）