Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes.
Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens.
Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores.
Is not required for early steps during B cell differentiation in the blood marrow.
Required for normal differentiation of B-1 cells (By similarity).
Required for normal B cell differentiation and proliferation in response to antigen challenges.
Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge.
宿主种属
小鼠(Mouse)
特异性
Human CD19
种属反应性
人(Human)
免疫原
NALM1 + NALM16 cells
阳性对照
Flow Cytometry: Human peripheral blood lymphocytes; Raji cells
偶联
AF405
Excitation(nm)
Violet Laser(405nm)
Emission(nm)
422nm
Ex/Em(nm)
Ex:401nm;Em:422nm
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
5 μL/test
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
2-8°C储存,避光,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
图片
Recombinant CD19 Antibody (AF405) (Ab223516) - Flow Cytometry Flow cytometry analysis of CD19 expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Human peripheral blood cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant CD19 Antibody (AF405) (Ab223516) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (AF405) (Ab190076).
Recombinant CD19 Antibody (AF405) (Ab223516) - Flow Cytometry Flow cytometry analysis of CD19 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Human peripheral blood cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant CD19 Antibody (AF405) (Ab223516) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF405) (Ab190076). Black - Unlabelled control, cells without incubation with primary antibody.
Recombinant CD19 Antibody (AF405) (Ab223516) - Flow Cytometry Flow cytometry analysis of CD19 expression by Raji cells (red) compared to an isotype control (blue). Cells were stained with Recombinant CD19 Antibody (AF405) (Ab223516) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF405) (Ab190076). Black - Unlabelled control, cells without incubation with primary antibody.
应用
应用名称
稀释比例
Flow Cytometry
5μl/test
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.
ZJ25F0926671
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