Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes.
Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens.
Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores.
Is not required for early steps during B cell differentiation in the blood marrow.
Required for normal differentiation of B-1 cells (By similarity).
Required for normal B cell differentiation and proliferation in response to antigen challenges.
Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge.
宿主种属
小鼠(Mouse)
特异性
Human CD19
种属反应性
人(Human)
免疫原
NALM1 + NALM16 cells
阳性对照
Flow Cytometry: Human peripheral blood lymphocytes; Raji cells
偶联
PE-Cy7
Excitation(nm)
Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm)
Emission(nm)
774nm
Ex/Em(nm)
Ex:565nm;Em:774nm
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
5 μL/test
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
2-8°C储存,避光,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
图片
Recombinant CD19 Antibody (PE-Cy7) (Ab223530) - Flow Cytometry Flow cytometry analysis of CD19 expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Cells were stained with Recombinant CD19 Antibody (PE-Cy7) (Ab223530) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (PE-Cy7) (Ab190079).
Recombinant CD19 Antibody (PE-Cy7) (Ab223530) - Flow Cytometry Flow cytometry analysis of CD19 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were stained with Recombinant CD19 Antibody (PE-Cy7) (Ab223530) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (PE-Cy7) (Ab190079). Black - Unlabelled control, cells without incubation with primary antibody.
应用
应用名称
稀释比例
Flow Cytometry
5μl/test
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.
ZJ25F0825876
危险品化学品经营许可证（带存储）