Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells.
Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man.
Binds to serum IgG.
Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells.
May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells.
May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
宿主种属
小鼠(Mouse)
特异性
CLEC4C
种属反应性
人(Human)
阳性对照
Flow Cytometry: Human peripheral mononuclear cells
偶联
PE
Excitation(nm)
Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm)
Emission(nm)
575nm
Ex/Em(nm)
Ex:565nm;Em:575nm
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
5 μL/test
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
2-8°C储存,避光,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Two-color flow cytometric analysis of CLEC4C/CD303 expression on human peripheral blood lymphocytes and monocytes. Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant IL3RA/CD123 Antibody (APC) (Ab223905) and either Mouse IgG (PE) (Ab180308; Left panel) or Recombinant CLEC4C/CD303 Antibody (PE) (Ab229446; Right panel) at 5μL/test.
应用
应用名称
稀释比例
Flow Cytometry
5μl/test
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.
ZJ26F0636413
危险品化学品经营许可证（带存储）