Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion.
Synthesizes the Ca2+ mobilizer nicotinate-adenine dinucleotide phosphate, NAADP+, from 2'-phospho-cADPR and nicotinic acid, as well as from NADP+ and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP+, while preferentially cleaving NADP+ to cADPR and ADPRP rather than into NADDP+.
Has cADPR hydrolase activity.
宿主种属
小鼠(Mouse)
特异性
Human CD38
种属反应性
人(Human)
免疫原
Fetal human thymocytes.
阳性对照
Flow Cytometry: Human peripheral blood monocytes
偶联
Biotin
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
0.5mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
2-8°C储存,避光,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
图片
Recombinant CD38 Antibody (Biotin) (Ab229452) - Flow Cytometry Flow cytometry analysis of CD38 expression by human peripheral blood cells (right panel) compared to an isotype control (left panel). Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant CD38 Antibody (Biotin) (Ab229452) at 0.1μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Left panel - Mouse IgG (Biotin) (Ab180306).
Recombinant CD38 Antibody (Biotin) (Ab229452) - Flow Cytometry Flow cytometry analysis of CD38 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant CD38 Antibody (Biotin) (Ab229452) at 0.1μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Blue - Mouse IgG (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.
Recombinant CD38 Antibody (Biotin) (Ab229452) - Flow Cytometry Flow cytometry analysis of CD38 expression by human peripheral blood monocytes (red) compared to an isotype control (blue). Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant CD38 Antibody (Biotin) (Ab229452) at 0.1μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Blue - Mouse IgG (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.
应用
应用名称
稀释比例
Flow Cytometry
≤0.3μg/test
For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume.
ZJ25F1028865
危险品化学品经营许可证（带存储）