Recombinant CD19 Antibody, clone P03D32, could be used for Flow Cytometry.
规格
产品名称
Recombinant CD19 Antibody (AF700)
别名
CD19抗体
英文别名
Antibody deficiency due to defect in CD19 antibody | Antibody deficiency due to defect in CD19, included antibody | AW495831 antibody | B lymphocyte antigen CD19 antibody | B lymphocyte surface antigen B4 antibody | B-lymphocyte antigen CD19 antibody | B-
规格或纯度
重组, ExactAb™, 已验证, 5 μL/test
生化机理
Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes (PubMed:29523808).
Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:1373518, PubMed:16672701, PubMed:2463100).
Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores (PubMed:12387743, PubMed:16672701, PubMed:9317126, PubMed:9382888).
Is not required for early steps during B cell differentiation in the blood marrow (PubMed:9317126).
Required for normal differentiation of B-1 cells (By similarity).
Required for normal B cell differentiation and proliferation in response to antigen challenges (PubMed:1373518, PubMed:2463100).
Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge (PubMed:12387743, PubMed:16672701, PubMed:9317126).
宿主种属
小鼠(Mouse)
特异性
CD19
种属反应性
人(Human)
阳性对照
Flow Cytometry: Human peripheral blood lymphocytes
偶联
AF700
Excitation(nm)
Red Laser(633nm)
Emission(nm)
719nm
Ex/Em(nm)
Ex:696nm;Em:719nm
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
5 μL/test
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂
0.05% Proclin300
储存条件
2-8°C储存,避光,禁止冷冻
运输条件
低温运输
稳定性与储存
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
图片
Recombinant DNA Damage Inducible Transcript 3 Antibody (Ab336571) - Western Blot
All lanes: Recombinant DNA Damage Inducible Transcript 3 Antibody (Ab336571) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 19 kDa
Observed band size: 29 kDa
Exposure time: 120.0 s
Recombinant DNA Damage Inducible Transcript 3 Antibody (Ab336571) - Western Blot
All lanes: Recombinant DNA Damage Inducible Transcript 3 Antibody (Ab336571) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 19 kDa
Observed band size: 29 kDa
Exposure time: 120.0 s
Recombinant DNA Damage Inducible Transcript 3 Antibody (Ab336571) - IHC
Immunohistochemical analysis of paraffin-embedded human breast cancer using Recombinant DNA Damage Inducible Transcript 3 Antibody (Ab336571) .
应用
应用名称
稀释比例
Flow Cytometry
5μl/test
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.