BI 653048 phosphate is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC 50 value of 55 nM. BI 653048 phosphate inhibits CP1A2, CYP2D6 , CYP2C9 , CYP2C19 and CYP3A4 isoforms’ activity and reduces affinity for the hERG ion channel ( IC 50 >30 μM). BI 653048 phosphate is extracted from patent WO2005028501A1 (Compound 103), is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus.