计算溶液所需的质量、体积或浓度。
活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
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B408735-1ml |
1ml |
现货 ![]() |
|
英文别名 | Cuscutin | Pyrano[3,2-c][2]benzopyran-6(2H)-one, 3,4,4a,10b-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-, (2R,3S,4S,4aR,10bS)- |
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规格或纯度 | 10mM in DMSO |
英文名称 | Bergenin |
生化机理 | 小檗苷(菟丝子苷)是三羟基苯甲酸的糖苷,也是 4-O-甲基没食子酸的 C-糖苷。 |
储存温度 | -80℃储存 |
运输条件 | 超低温冰袋运输 |
产品介绍 |
溶于醇。无臭,味苦,遇光和受热渐渐变色。 Information Bergenin (Cuscutin) is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid. In vivo
cell lines: Concentrations: Incubation Time: Powder Purity:≥99% |
ALogP | -0.849 |
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hba_count | 4 |
HBD Count | 5 |
Rotatable Bond | 2 |
Canonical SMILES | COC1=C(O)C2=C(C=C1O)C(=O)OC3C(O)C(O)C(CO)OC23 |
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分子量 | 328.27 |
Reaxy-Rn | 1354737 |
Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1354737&ln= |
DMSO(mg / mL) Max Solubility | 66 |
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DMSO(mM) Max Solubility | 201.05 |
Water(mg / mL) Max Solubility | <1 |
Reaxy-Rn | 1354737 |
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Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1354737&ln= |
Concentration | 9-11(mmol/L) |
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Infrared spectrum | Conforms to Structure |
1. Huang Dan, Sun Chaoqun, Chen Min, Bai Shuyou, Zhao Xuanna, Wang Weiming, Geng Kang, Huang Wenbo, Zhao Tingting, Wu Bin, Zhang Guilin, Wu Dong, Xu Youhua. (2022) Bergenin ameliorates airway inflammation and remodeling in asthma by activating SIRT1 in macrophages to regulate the NF-κB pathway. Frontiers in Pharmacology, 13 [PMID:36313381] [10.3389/fphar.2022.994878] |
2. Yinggui Zhu, Lili Zou, Qin Dong, Derong Jiang. (2015) Determination of bergenin based on the electrochemiluminescence quenching of tris(2,2′-bipyridine)-ruthenium(II). LUMINESCENCE, 30 (8): (1269-1273). [PMID:25808319] [10.1002/bio.2891] |
1. Huang Dan, Sun Chaoqun, Chen Min, Bai Shuyou, Zhao Xuanna, Wang Weiming, Geng Kang, Huang Wenbo, Zhao Tingting, Wu Bin, Zhang Guilin, Wu Dong, Xu Youhua. (2022) Bergenin ameliorates airway inflammation and remodeling in asthma by activating SIRT1 in macrophages to regulate the NF-κB pathway. Frontiers in Pharmacology, 13 [PMID:36313381] [10.3389/fphar.2022.994878] |
2. Yinggui Zhu, Lili Zou, Qin Dong, Derong Jiang. (2015) Determination of bergenin based on the electrochemiluminescence quenching of tris(2,2′-bipyridine)-ruthenium(II). LUMINESCENCE, 30 (8): (1269-1273). [PMID:25808319] [10.1002/bio.2891] |