Rho相关蛋白激酶1（ROCK1）
热门产品
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GSK-25期货 货号: G649634查看产品价格与包装技术标识符
- IUPAC名称
- 4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-yl)-N-(6-fluoro-1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
- SMILES
- CC1=C(C(N=C(N1)C2=CC(=NC=C2)Cl)C3=C(C=C(C=C3)Cl)F)C(=O)NC4=C(C=C5C(=C4)C=NN5)F
- InChIKey
- KZYAHEIPPAPADQ-UHFFFAOYSA-N
- InChI
- 1S/C24H16Cl2F2N6O/c1-11-21(24(35)32-19-6-13-10-30-34-18(13)9-17(19)28)22(15-3-2-14(25)8-16(15)27)33-23(31-11)12-4-5-29-20(26)7-12/h2-10,22H,1H3,(H,30,34)(H,31,33)(H,32,35)
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![4-[1-(Cyclopropylmethyl)-1H-benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/C/6/C668331.jpg)
4-[1-(Cyclopropylmethyl)-1H-benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine分子式: C13H13N5O 分子量: 255.28期货 货号: C668331查看产品价格与包装技术标识符
- IUPAC名称
- 4-[1-(cyclopropylmethyl)benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine
- SMILES
- C1CC1CN2C3=CC=CC=C3N=C2C4=NON=C4N
- InChIKey
- LLDVRUBUBPSOMY-UHFFFAOYSA-N
- InChI
- 1S/C13H13N5O/c14-12-11(16-19-17-12)13-15-9-3-1-2-4-10(9)18(13)7-8-5-6-8/h1-4,8H,5-7H2,(H2,14,17)
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4-((2-Amino-4-pyrimidinyl)amino)benzenesulfonamide期货 货号: A667885查看产品价格与包装技术标识符
- IUPAC名称
- 4-[(2-aminopyrimidin-4-yl)amino]benzenesulfonamide
- SMILES
- C1=CC(=CC=C1NC2=NC(=NC=C2)N)S(=O)(=O)N
- InChIKey
- QOAXQANKSMHFKJ-UHFFFAOYSA-N
- InChI
- 1S/C10H11N5O2S/c11-10-13-6-5-9(15-10)14-7-1-3-8(4-2-7)18(12,16)17/h1-6H,(H2,12,16,17)(H3,11,13,14,15)
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![4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/E/6/E669231.jpg)
4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine期货 货号: E669231查看产品价格与包装技术标识符
- IUPAC名称
- 4-(1-ethylimidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
- SMILES
- CCN1C2=C(C=NC=C2)N=C1C3=NON=C3N
- InChIKey
- UGHABJRZQKZAHP-UHFFFAOYSA-N
- InChI
- 1S/C10H10N6O/c1-2-16-7-3-4-12-5-6(7)13-10(16)8-9(11)15-17-14-8/h3-5H,2H2,1H3,(H2,11,15)
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![[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/A/6/A669204.jpg)
[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone分子式: C15H18N8O2 分子量: 342.36期货 货号: A669204查看产品价格与包装技术标识符
- IUPAC名称
- [2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone
- SMILES
- CCN1C2=C(C=NC=C2C(=O)N3CCC(C3)N)N=C1C4=NON=C4N
- InChIKey
- PHWHNHYZZNJPLB-QMMMGPOBSA-N
- InChI
- 1S/C15H18N8O2/c1-2-23-12-9(15(24)22-4-3-8(16)7-22)5-18-6-10(12)19-14(23)11-13(17)21-25-20-11/h5-6,8H,2-4,7,16H2,1H3,(H2,17,21)/t8-/m0/s1
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![N-(7-chloro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/N/6/N669161.jpg)
N-(7-chloro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide期货 货号: N669161查看产品价格与包装技术标识符
- IUPAC名称
- N-(7-chloro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide
- SMILES
- CC1=C(C(CC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=CC4=C(C(=C3)Cl)NN=C4
- InChIKey
- OYNBTBJATZVIGH-UHFFFAOYSA-N
- InChI
- 1S/C21H16ClF3N4O2/c1-10-18(20(31)28-14-6-12-9-26-29-19(12)16(22)7-14)15(8-17(30)27-10)11-2-4-13(5-3-11)21(23,24)25/h2-7,9,15H,8H2,1H3,(H,26,29)(H,27,30)(H,28,31)
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![6-(3-methyl-1H-pyrazol-4-yl)-2-[(2R)-quinuclidin-2-yl]-3H-thieno[3,2-d]pyrimidin-4-one](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/M/6/M669834.jpg)
6-(3-methyl-1H-pyrazol-4-yl)-2-[(2R)-quinuclidin-2-yl]-3H-thieno[3,2-d]pyrimidin-4-oneCAS: 1330782-69-8 分子式: C17H19N5OS期货 货号: M669834查看产品价格与包装技术标识符
- IUPAC名称
- 2-[(2R)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)-3H-thieno[3,2-d]pyrimidin-4-one
- SMILES
- CC1C(=CNN=1)C2=CC3=C(S2)C(=O)NC(=N3)[C@@H]4N5CCC(CC5)C4
- InChIKey
- XGVXKJKTISMIOW-CYBMUJFWSA-N
- InChI
- 1S/C17H19N5OS/c1-9-11(8-18-21-9)14-7-12-15(24-14)17(23)20-16(19-12)13-6-10-2-4-22(13)5-3-10/h7-8,10,13H,2-6H2,1H3,(H,18,21)(H,19,20,23)/t13-/m1/s1
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![4-(1-乙基-1H-苯并[d]咪唑-2-基)-1，2，5-恶二唑-3-胺](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/O/7/O769616.jpg)
4-(1-乙基-1H-苯并[d]咪唑-2-基)-1，2，5-恶二唑-3-胺期货 货号: O769616查看产品价格与包装技术标识符
- IUPAC名称
- 4-(1-ethylbenzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
- SMILES
- CCN1C2=CC=CC=C2N=C1C3=NON=C3N
- InChIKey
- HCRQPXYLXXLKPT-UHFFFAOYSA-N
- InChI
- 1S/C11H11N5O/c1-2-16-8-6-4-3-5-7(8)13-11(16)9-10(12)15-17-14-9/h3-6H,2H2,1H3,(H2,12,15)
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N-(1H-indazol-5-yl)-2-methyl-4-(naphthalen-2-yl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxamideCAS: 864082-23-5 分子式: C24H20N4O2 分子量: 396.4期货 货号: N1303470查看产品价格与包装技术标识符
- IUPAC名称
- N-(1H-indazol-5-yl)-6-methyl-4-naphthalen-2-yl-2-oxo-3,4-dihydro-1H-pyridine-5-carboxamide
- SMILES
- CC1=C(C(CC(=O)N1)C2=CC3=CC=CC=C3C=C2)C(=O)NC4=CC5=C(C=C4)NN=C5
- InChIKey
- ODLNBFNBEPOFNC-UHFFFAOYSA-N
- InChI
- 1S/C24H20N4O2/c1-14-23(24(30)27-19-8-9-21-18(11-19)13-25-28-21)20(12-22(29)26-14)17-7-6-15-4-2-3-5-16(15)10-17/h2-11,13,20H,12H2,1H3,(H,25,28)(H,26,29)(H,27,30)
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N-(4-pyridin-4-yl-1,3-thiazol-2-yl)-2,3-dihydro-1,4-benzodioxine-3-carboxamideCAS: 681173-76-2 分子式: C17H13N3O3S 分子量: 339.4期货 货号: N1295812查看产品价格与包装技术标识符
- IUPAC名称
- N-(4-pyridin-4-yl-1,3-thiazol-2-yl)-2,3-dihydro-1,4-benzodioxine-3-carboxamide
- SMILES
- C1C(OC2=CC=CC=C2O1)C(=O)NC3=NC(=CS3)C4=CC=NC=C4
- InChIKey
- QKKGSTFAKMXWFE-UHFFFAOYSA-N
- InChI
- 1S/C17H13N3O3S/c21-16(15-9-22-13-3-1-2-4-14(13)23-15)20-17-19-12(10-24-17)11-5-7-18-8-6-11/h1-8,10,15H,9H2,(H,19,20,21)
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常见问题
Rho相关蛋白激酶1（ROCK1）分类下有哪些产品？
该分类汇集了蛋白激酶(Protein kinases)板块中与Rho相关蛋白激酶1（ROCK1）相关的化合物，包括抑制剂、激动剂或拮抗剂以及参考工具化合物。每个条目均提供结构、CAS号和已报道的活性数据，便于您在订购前确认注释信息。
为Rho相关蛋白激酶1（ROCK1）挑选化合物时应考虑什么？
需考虑Rho相关蛋白激酶1（ROCK1）下各化合物已报道的效价及其检测方法、对高度相关靶点的选择性、细胞实验所需的通透性，以及在您所用缓冲液中的稳定性。两个化学结构不同的化合物给出相同表型，其证据强度远高于单一化合物。
Rho相关蛋白激酶1（ROCK1）相关化合物提供哪些质量信息？
各Rho相关蛋白激酶1（ROCK1）产品页面均列出纯度、结构确证数据、分子式与分子量以及储存条件，并可提供批次专属分析证书。溶解性和操作说明见产品说明书。所有产品仅供专业研发用途，不得用于人体、动物、诊断或治疗。
可以按活性或结构搜索Rho相关蛋白激酶1（ROCK1）相关化合物吗？
可以。您可在Rho相关蛋白激酶1（ROCK1）分类中按作用机制（抑制剂、激动剂、拮抗剂）筛选，并按靶点名称或基因符号、CAS号、分子式或SMILES搜索精确结构及相似类似物。大包装或未收录产品请联系 compliance@aladdinsci.com。
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