Human chymase has been used in a study to assess the effects of Panax notoginseng flower extract on the TGF-β/Smad signal transduction pathway in heart remodeling. Human chymase has also been used in a study to investigate the blood glucose level and survival in streptozotocin-treated human chymase transgenic mice.
Chymase has been implicated in generation of angiotensin II and cleavage of big endothelin. Studies indicate it may be involved in vascular proliferation, myocardial infarction and dermatitis.
规格
产品名称
胃促胰酶 人
规格或纯度
重组, recombinant, expressed in Pichia pastoris
生化机理
该酶可迅速将血管紧张素 I 转化为血管紧张素 II。酶活性的最适 pH 值为 7.5 ~ 9.0。大豆胰蛋白酶抑制剂、苯甲基磺酰氟和糜蛋白酶抑制剂可抑制酶的活性。