DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-dependent protein kinase ( DNA-PK ) is a DNA-PK enzyme complex composed of Ku70/Ku80 heterodimer and DNA-dependent protein kinase catalytic subunit (DNA-PKcs). DNA-PK-IN-1 has the potential for the research of cancer diseases (extracted from patent WO2021136463A1, compound 1).