Dendrogenin A (DDA) is a ligand for liver X receptor ( LXR ) , that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor , thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC 50 of 4.1 and 6.2 µM. Dendrogenin A arrests the cell cycle at G0/G1 phase.