DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.

规格

规格或纯度

Moligand™, 10 mM in DMSO

英文名称

DM-β-CD

储存条件

-80℃储存

运输条件

特低温运输

名称和识别符

分子类型

小分子

Isomeric SMILES

COC[C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)OC)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)OC)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)OC)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)OC)O[C@@H]7[C@H](O[C@@H]([C@@H]([C@H]7O)OC)O[C@@H]8[C@H](O[C@H](O2)[C@@H]([C@H]8O)OC)COC)COC)COC)COC)COC)COC)OC)O

分子量

1331.36

Beilstein号

1679140

Reaxy-Rn

16858380

Reaxys-RN link address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=16858380&ln=

技术文档

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🔬 规格说明书

该级别的完整质量属性和验收标准。

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高级数据

化学和物理性质

闪点(℃)

187°C

熔点

180-182°C

安全和危险性（GHS）

WGK Germany

个人防护装备

Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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技术文档和文章

环糊精全解：结构与包合机理、改性类型、选型与应用速查（附5类清单）

目录：技术文章

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环糊精

Cyclodextrins, Explained: Structure, Inclusion Mechanism, Derivatization Types, and a Quick Selection Guide (with a 5-Category Checklist)

目录：技术文章

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Cyclodextrins

此产品的引用文献

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引用文献

1. Hang Li, Qing-Sheng Zhao, Li-Wei Wang, Sen-Lin Chang, Pei-Dong Wang, Bing Zhao. (2022) Optimization of cyclodextrin-assisted green extraction of cannabidiol from industrial hemp leaves: Release behavior, permeability, bioactivity, and stability. INDUSTRIAL CROPS AND PRODUCTS, [10.1016/j.indcrop.2022.115709]
2. Hang Li, Qing-Sheng Zhao, Sen-Lin Chang, Tan-Ran Chang, Ming-Hui Tan, Bing Zhao. (2021) Development of cannabidiol full-spectrum oil/2,6-di-O-methyl-β-cyclodextrin inclusion complex with enhanced water solubility, bioactivity, and thermal stability. JOURNAL OF MOLECULAR LIQUIDS, [10.1016/j.molliq.2021.118318]
3. Liyuan Chen, Waixiang Yang, Chuanzhu Gao, Xiali Liao, Jing Yang, Bo Yang. (2021) The complexes of cannabidiol mediated by bridged cyclodextrins dimers with high solubilization, in vitro antioxidant activity and cytotoxicity. JOURNAL OF MOLECULAR LIQUIDS, [10.1016/j.molliq.2021.117017]
4. Hang Li, Sen-Lin Chang, Tan-Ran Chang, Ying You, Xiao-Dong Wang, Li-Wei Wang, Xiao-Fan Yuan, Ming-Hui Tan, Pei-Dong Wang, Peng-Wei Xu, Wei-Bo Gao, Qing-Sheng Zhao, Bing Zhao. (2021) Inclusion complexes of cannabidiol with β-cyclodextrin and its derivative: Physicochemical properties, water solubility, and antioxidant activity. JOURNAL OF MOLECULAR LIQUIDS, [10.1016/j.molliq.2021.116070]
5. Ying Chen, Yongchao Yao, Xueying Zhou, Chunyan Liao, Xin Dai, Jie Liu, Yunlong Yu, Shiyong Zhang. (2019) Cascade-Reaction-Based Nanodrug for Combined Chemo/Starvation/Chemodynamic Therapy against Multidrug-Resistant Tumors. ACS Applied Materials & Interfaces, [PMID:31722522] [10.1021/acsami.9b15848]
6. Xiaoxu Du, Nan Song, Ying-Wei Yang, Guolin Wu, Jianbiao Ma, Hui Gao. (2014) Reverse micelles based on β-cyclodextrin-incorporated amphiphilic polyurethane copolymers for protein delivery. Polymer Chemistry, 5 (18): (5300-5309). [10.1039/C4PY00278D]
7. Pu Zheng, Xinru Chen, Chunyang Zhao, Jialong Wang, Jianhong Zhang, Xiong Hu, Wenchao Geng, Qianqian Zhao. (2024) Integrating strategy to investigate the formation and stabilization mechanisms of Curcumin-Cyclodextrin inclusion complexes: Experimental characterizations and multi-scale computational simulations. FOOD HYDROCOLLOIDS, [10.1016/j.foodhyd.2024.110679]