| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| D276597-100μg |
100μg |
现货  |
|
| 英文别名 | 4,5-Diaminofluorescein | 2-(3,6-Dihydroxy-9H-xanthen-9-yl)-4,5-diamino-benzoic acid | DTXSID60443252 | AS-78359 | 5,6-Diamino-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one | DAF-2-CAS 205391-01-1-Calbiochem | Spiro[isobenzofuran-1(3H),9'-[9H] |
|---|---|
| 规格或纯度 | 5 mM in DMSO |
| 英文名称 | DAF-2 (DMSO solution) |
| 生化机理 | 荧光一氧化氮探针。DAF-2解决方案。在氧气存在下与NO反应生成高度荧光的三唑并荧光素DAF-2T。确定一氧化氮合酶活性。防渗膜DAF-2 DA（ab14；Fluorescent indicator for the direct detection of nitric oxide (NO) in vitro. |
| 储存温度 | 避光,干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 备注 | 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 |
| 产品介绍 |
储存在-20℃。存放在黑暗中。存放在干燥的条件下。该产品对空气和光敏感，空气氧化或微生物代谢可能会产生杂质。 Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. description： A highly sensitive and specific fluorescent indicator for the direct detection of nitric oxide (NO) in vitro. The relatively non-fluorescent DAF-2 reacts rapidly with NO in the presence of oxygen to yield the highly fluorescent triazolofluorescein compound (DAF-2T). Can detect NO under neutral conditions (detection limit = 5 nM). A highly sensitive and specific fluorescent indicator for the direct detection of nitric oxide (NO) in vivo. The relatively non-fluorescent DAF-2 reacts rapidly with NO in the presence of oxygen to yield the highly fluorescent compound triazolofluorescein (DAF-2 T). Can detect NO under neutral conditions (detection limit = 5 nM). Excitation maximum: 495 nm; emission maximum: 515 nm. |
| IUPAC Name | 5,6-diamino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one |
|---|---|
| INCHI | InChI=1S/C20H14N2O5/c21-15-7-11-14(8-16(15)22)20(27-19(11)25)12-3-1-9(23)5-17(12)26-18-6-10(24)2-4-13(18)20/h1-8,23-24H,21-22H2 |
| InChi Key | LTYUPYUWXRTNFQ-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC2=C(C=C1O)OC3=C(C24C5=CC(=C(C=C5C(=O)O4)N)N)C=CC(=C3)O |
| Isomeric SMILES | C1=CC2=C(C=C1O)OC3=C(C24C5=CC(=C(C=C5C(=O)O4)N)N)C=CC(=C3)O |
| 分子量 | 362.34 |
| Reaxy-Rn | 8014486 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8014486&ln= |
| 溶解性 | Supplied in DMSO (5 mM) |
|---|---|
| 敏感性 | 对空气和光敏感 |
| 分子量 | 362.300 g/mol |
| XLogP3 | 2.100 |
| 氢键供体数Hydrogen Bond Donor Count | 4 |
| 氢键受体数Hydrogen Bond Acceptor Count | 7 |
| 可旋转键计数Rotatable Bond Count | 0 |
| 精确质量Exact Mass | 362.09 Da |
| 单同位素质量Monoisotopic Mass | 362.09 Da |
| 拓扑极表面积Topological Polar Surface Area | 128.000 Ų |
| 重原子数Heavy Atom Count | 27 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 589.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| Concentration(in DMSO) | 4.5-5.5（mmol/L） |
|---|---|
| Record the entire process by video | Conform |
| Appearance(Orange to Yellow Liquid) | Pass |
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 I2207216 |
分析证书 | 23-06-15 | D276597 |
| 1. Shuang-Shuang Wan, Jin-Yue Zeng, Han Cheng, Xian-Zheng Zhang. (2018) ROS-induced NO generation for gas therapy and sensitizing photodynamic therapy of tumor. BIOMATERIALS, 185 (51). [PMID:30218836] [10.1016/j.biomaterials.2018.09.004] |
| 1. Shuang-Shuang Wan, Jin-Yue Zeng, Han Cheng, Xian-Zheng Zhang. (2018) ROS-induced NO generation for gas therapy and sensitizing photodynamic therapy of tumor. BIOMATERIALS, 185 (51). [PMID:30218836] [10.1016/j.biomaterials.2018.09.004] |
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