计算溶液所需的质量、体积或浓度。
EGFR-IN-119 (Compound 5l) is an inhibitor for EGFR with an IC 50 of 84.3 nM. EGFR-IN-119 inhibits the cytotoxicity in lung cancer cell A549 with an IC 50 of 1.34 μM. EGFR-IN-119 downregulates the expressions of EGFR , KRAS, and MAP2K genes, exhibits antioxidant activity through reduction of reactive oxygen species ( ROS ), and hyperpolarizes the mitochondrial membrane potential.