基本描述

别名	4-氟苯甲胺 \| 对氟苄胺,对氟苯甲胺,4-氟苯甲胺
英文别名	4-fluoro-benzene methanamine \| 4-Flourobenzyl amine \| MFCD00008120 \| SCHEMBL2532551 \| Z54748266 \| STK862565 \| 1-(4-fluorophenyl)methanamine \| (4-fluorobenzyl) amine \| F0252 \| AC-9771 \| C7H8FN \| A22214 \| [(4-fluorophenyl)methyl]amine \| EINECS 205-430-4 \| F
规格或纯度	≥99%
英文名称	4-Fluorobenzylamine
储存温度	充氩
运输条件	常规运输
产品介绍	18F]4-氟苄胺与叶酸的α-和γ-羧基反应，形成18F-标记的叶酸。它是合成18F-标记化合物的重要结构单元. 抗过敏药物阿司咪唑，镇痛药Flupirine的中间体。 4-氟苄胺被用于合成3-羟基-4-吡啶酮配体的新型三-铁(III)螯合物. [18F]4-fluorobenzylamine reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate. It is an important building block for the synthesis of 18F-labeled compounds 4-Fluorobenzylamine was used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands.

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关联靶点（人）

PRSS1 Tclin Trypsin I (2306 活性数据)

点击查看靶蛋白信息： PRSS1

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PNMT Tchem Phenylethanolamine N-methyltransferase (540 活性数据)

点击查看靶蛋白信息： PNMT

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KAT8 Tchem Histone acetyltransferase KAT8 (178 活性数据)

点击查看靶蛋白信息： KAT8

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

AOC3 Amine oxidase, copper containing (44 活性数据)

点击查看靶蛋白信息： AOC3

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus epidermidis (22802 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	488183927
EC号	205-430-4
分子类型	小分子
IUPAC Name	(4-fluorophenyl)methanamine
INCHI	InChI=1S/C7H8FN/c8-7-3-1-6(5-9)2-4-7/h1-4H,5,9H2
InChi Key	IIFVWLUQBAIPMJ-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC=C1CN)F
Isomeric SMILES	C1=CC(=CC=C1CN)F
WGK Germany	3
PubChem CID	67326
UN Number	2735
分子量	125.14
Beilstein号	636501
Reaxy-Rn	636501

化学和物理性质

溶解性	可溶于水
密度	1.095
敏感性	对空气敏感
折光率	1.512
闪点(℉)	150.8 °F
闪点(℃)	66 °C
沸点	183°C
分子量	125.140 g/mol
XLogP3	1.100
氢键供体数Hydrogen Bond Donor Count	1
氢键受体数Hydrogen Bond Acceptor Count	2
可旋转键计数Rotatable Bond Count	1
精确质量Exact Mass	125.064 Da
单同位素质量Monoisotopic Mass	125.064 Da
拓扑极表面积Topological Polar Surface Area	26.000 Å²
重原子数Heavy Atom Count	9
形式电荷Formal Charge	0
复杂度Complexity	77.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS05
信号词	Danger
危险声明	H314: 造成严重的皮肤灼伤和眼睛损伤
预防措施声明	P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P301+P330+P331: 如误吞咽：漱口。不要诱导呕吐。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P363: 再次使用之前，请清洗受污染的衣物。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P302+P361+P354: 如果接触皮肤：立即脱掉所有被污染的衣服。立即用水冲洗几分钟。 P316: 立即寻求紧急医疗救助。
WGK Germany	3
Reaxy-Rn	636501
个人防护装备	Faceshields,full-face respirator (US),Gloves,Goggles,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

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找到11个结果

批号(Lot Number)	证书类型	日期	货号
L2024171	分析证书	24-10-12	F111212
A2305173	分析证书	23-01-13	F111212
B2225887	分析证书	22-01-19	F111212
B2225889	分析证书	22-01-19	F111212
B2225890	分析证书	22-01-19	F111212
B2225891	分析证书	22-01-19	F111212
B2317420	分析证书	22-01-19	F111212
B2317421	分析证书	22-01-19	F111212
I2308178	分析证书	22-01-19	F111212
L2410080	分析证书	22-01-19	F111212
G2311075	分析证书	21-03-29	F111212

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此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?

1. Guijun Yan, Guomin Sui, Wentao Chen, Kuo Su, Yaqing Feng, Bao Zhang. (2022) Selectively Fluorinated Benzylammonium-Based Spacer Cation Enables Graded Quasi-2D Perovskites for Efficient and Stable Solar Cells. CHEMISTRY OF MATERIALS, 34 (7): (3346–3356). [10.1021/acs.chemmater.2c00146]
2. Chuanchuan Zhao, Yongjun Gao, Ziyi Zhang, Ding Ma. (2020) Functions of Phytic Acid in Fabricating Metal-Free Carbocatalyst for Oxidative Coupling of Benzylamines†. CHINESE JOURNAL OF CHEMISTRY, 38 (11): (1292-1298). [10.1002/cjoc.202000145]
3. Pengqi Zhu, Jin Zhang, Jie Wang, Peng Kong, Yunwei Wang, Zhanfeng Zheng. (2020) Photocatalytic selective aerobic oxidation of amines to nitriles over Ru/γ-Al2O3: the role of the support surface and the strong imine intermediate adsorption. Catalysis Science & Technology, 10 (2): (440-449). [10.1039/C9CY01916B]
4. Yingfeng Xu, Zhipeng Ge, Xueqin Zhang, Huajun Feng, Xianbin Ying, Baocheng Huang, Dongsheng Shen, Meizhen Wang, Yuyang Zhou, Yanfeng Wang, Hanqing Yu. (2019) Validation of effective roles of non-electroactive microbes on recalcitrant contaminant degradation in bioelectrochemical systems. ENVIRONMENTAL POLLUTION, 249 (794). [PMID:30951963] [10.1016/j.envpol.2019.03.036]
5. Hailong Xu, Hong Zhou, Lu Feng, Qiaoyun Wang, Rui Chen, Wentao Huang, Xixi Wu. (2018) Synthesis, crystal structures, and magnetic properties of six transition metal phosphonates. DALTON TRANSACTIONS, 47 (32): (11226-11238). [PMID:30052240] [10.1039/C8DT02070A]
6. Jun Dai, Juan Yang, Xiaohan Wang, Lei Zhang, Yingjie Li. (2015) Enhanced visible-light photocatalytic activity for selective oxidation of amines into imines over TiO2(B)/anatase mixed-phase nanowires. APPLIED SURFACE SCIENCE, 349 (343). [10.1016/j.apsusc.2015.04.232]
7. Huajun Feng, Xueqin Zhang, Kun Guo, Eleni Vaiopoulou, Dongsheng Shen, Yuyang Long, Jun Yin, Meizhen Wang. (2015) Electrical Stimulation Improves Microbial Salinity Resistance and Organofluorine Removal in Bioelectrochemical Systems. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81 (11): [PMID:25819966] [10.1128/AEM.04066-14]
8. Huajun Feng, Xueqin Zhang, Yuxiang Liang, Meizhen Wang, Dongsheng Shen, Yangcheng Ding, Baocheng Huang, Jiali Shentu. (2014) Enhanced removal of p-fluoronitrobenzene using bioelectrochemical system. WATER RESEARCH, 60 (54). [PMID:24821195] [10.1016/j.watres.2014.03.027]

参考文献

1. Fantoni ER, Dal Ben D, Falzoni S, Di Virgilio F, Lovestone S, Gee A. (2017) Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel ¹⁸F-labelled PET tracer targeting P2X7.. EJNMMI Res, 7 (1): (31). [PMID:28374288] [10.1021/op500134e]
2. Francesc Yraola, Silvia García-Vicente, Juan Fernandez-Recio, Fernando Albericio, Antonio Zorzano, Luc Marti, Miriam Royo,. (2006-10-13) New efficient substrates for semicarbazide-sensitive amine oxidase/VAP-1 enzyme: analysis by SARs and computational docking.. Journal of medicinal chemistry, 49 ((21)): ( 6197-6208 ). [PMID:17034126]
3. Jenilee Way,Frank Wuest. (2013-01-12) Fully automated synthesis of 4-[18F]fluorobenzylamine based on borohydride/NiCl2 reduction.. Nuclear medicine and biology, 40 ((3)): (430-436). [PMID:23306136]
4. Guoqing Cheng,Yan Liu,Tao Chen,Wenjing Chen,Zhibin Fang,Ji Zhang,Liming Ding,Xinhua Li,Tongfei Shi,Zhengguo Xiao. (2020-03-25) Efficient All-Inorganic Perovskite Light-Emitting Diodes with Improved Operation Stability.. ACS applied materials & interfaces, 12 ((15)): (18084-18090). [PMID:32204590]
5. Walkiria Schlindwein,Emma Waltham,John Burgess,Norman Binsted,Ana Nunes,Andreia Leite,Maria Rangel. (2006-03-01) New lipophilic 3-hydroxy-4-pyridinonate iron(III) complexes: synthesis and EXAFS structural characterisation.. Dalton transactions (Cambridge, England : 2003), (10) ((10)): (1313-1321). [PMID:16505910]
6. Ingrid Koslowsky,John Mercer,Frank Wuest. (2010-08-27) Synthesis and application of 4-[(18)F]fluorobenzylamine: A versatile building block for the preparation of PET radiotracers.. Organic & biomolecular chemistry, 8 ((20)): (4730-4735). [PMID:20740244]
7. Muhammad Kaleem Khosa,Muhammad Asghar Jamal,Muhammad Jawad Saif,Majid Muneer,Fazalur Rehman,Muhammad Farman,Hafiz Muhammad Shoaib,Muhammad Shahid,Shabnam Hameed. (2015-12-08) Synthesis, Spectral investigation (¹H, ¹³C) and Anti-microbial Screening of benzophenone imines.. Pakistan journal of pharmaceutical sciences, 28 ((6)): (2167-2171). [PMID:26639485]
8. Guijun Yan, Guomin Sui, Wentao Chen, Kuo Su, Yaqing Feng, Bao Zhang. (2022) Selectively Fluorinated Benzylammonium-Based Spacer Cation Enables Graded Quasi-2D Perovskites for Efficient and Stable Solar Cells. CHEMISTRY OF MATERIALS, 34 (7): (3346–3356). [10.1021/acs.chemmater.2c00146]
9. Chuanchuan Zhao, Yongjun Gao, Ziyi Zhang, Ding Ma. (2020) Functions of Phytic Acid in Fabricating Metal-Free Carbocatalyst for Oxidative Coupling of Benzylamines†. CHINESE JOURNAL OF CHEMISTRY, 38 (11): (1292-1298). [10.1002/cjoc.202000145]
10. Pengqi Zhu, Jin Zhang, Jie Wang, Peng Kong, Yunwei Wang, Zhanfeng Zheng. (2020) Photocatalytic selective aerobic oxidation of amines to nitriles over Ru/γ-Al2O3: the role of the support surface and the strong imine intermediate adsorption. Catalysis Science & Technology, 10 (2): (440-449). [10.1039/C9CY01916B]
11. Yingfeng Xu, Zhipeng Ge, Xueqin Zhang, Huajun Feng, Xianbin Ying, Baocheng Huang, Dongsheng Shen, Meizhen Wang, Yuyang Zhou, Yanfeng Wang, Hanqing Yu. (2019) Validation of effective roles of non-electroactive microbes on recalcitrant contaminant degradation in bioelectrochemical systems. ENVIRONMENTAL POLLUTION, 249 (794). [PMID:30951963] [10.1016/j.envpol.2019.03.036]
12. Hailong Xu, Hong Zhou, Lu Feng, Qiaoyun Wang, Rui Chen, Wentao Huang, Xixi Wu. (2018) Synthesis, crystal structures, and magnetic properties of six transition metal phosphonates. DALTON TRANSACTIONS, 47 (32): (11226-11238). [PMID:30052240] [10.1039/C8DT02070A]
13. Jun Dai, Juan Yang, Xiaohan Wang, Lei Zhang, Yingjie Li. (2015) Enhanced visible-light photocatalytic activity for selective oxidation of amines into imines over TiO2(B)/anatase mixed-phase nanowires. APPLIED SURFACE SCIENCE, 349 (343). [10.1016/j.apsusc.2015.04.232]
14. Huajun Feng, Xueqin Zhang, Kun Guo, Eleni Vaiopoulou, Dongsheng Shen, Yuyang Long, Jun Yin, Meizhen Wang. (2015) Electrical Stimulation Improves Microbial Salinity Resistance and Organofluorine Removal in Bioelectrochemical Systems. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81 (11): [PMID:25819966] [10.1128/AEM.04066-14]
15. Huajun Feng, Xueqin Zhang, Yuxiang Liang, Meizhen Wang, Dongsheng Shen, Yangcheng Ding, Baocheng Huang, Jiali Shentu. (2014) Enhanced removal of p-fluoronitrobenzene using bioelectrochemical system. WATER RESEARCH, 60 (54). [PMID:24821195] [10.1016/j.watres.2014.03.027]

溶液计算器

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货号 (SKU)	包装规格	是否现货
F111212-5g	5g	现货
F111212-10g	10g	现货
F111212-25g	25g	现货
F111212-100g	100g	现货
F111212-500g	500g	现货

4-氟苄胺

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基本描述

AI解读

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器