Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC 50 of 2.2 μM
In Vitro
Fumarate hydratase-IN-1 inhibits SW620, ACHN, HCT-116, PC3, and SK-MEL-28 cell lines with a mean IC 50 of 2.2 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:Fumarate hydratase
规格
别名
富马酸水合酶-IN-1
规格或纯度
10mM in DMSO
英文名称
Fumarate hydratase-IN-1
生化机理
富马酸氢化酶-IN-1(化合物 2)是一种细胞渗透性富马酸氢化酶抑制剂。富马酸氢化酶-IN-1 对几种癌细胞株具有抗增殖活性,平均 IC 50 为 2.2 μM。