1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester FAQs
1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester FAQs
1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester is a nitrogen-containing heterocyclic ester compound widely used as a synthetic intermediate in pharmaceutical and fine-chemical research.
- Chemical Name
- 1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester
- SKU / Product Code
- E725556
- Compound Class
- Piperidine-4-carboxylic acid ester (N-alkylated piperidine derivative)
- Primary Application
- Synthetic intermediate for pharmaceutical and medicinal chemistry research
- Functional Groups
- Tertiary amine (piperidine N), ester (ethyl ester)
- Supplier
- Aladdin Scientific
What Is 1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester?
1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester (SKU: E725556) is an N-alkylated piperidine derivative bearing an ethyl ester group at the 4-position of the piperidine ring. Also referred to as ethyl 1-ethylpiperidine-4-carboxylate, the compound contains two key functional groups: a tertiary amine within the saturated six-membered nitrogen heterocycle and an ethyl ester at the ring's 4-position. This combination makes it a versatile building block in synthetic organic chemistry, particularly in the preparation of pharmacologically active piperidine-based scaffolds.
The compound is supplied by Aladdin Scientific for research and development use. Researchers should consult the product's Safety Data Sheet (SDS) and Certificate of Analysis (CoA) for confirmed physicochemical data, purity specifications, and handling requirements specific to the supplied lot.
Handling, Storage, and Safety
As with all laboratory reagents containing a tertiary amine and ester functionality, 1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester should be handled under standard laboratory safety practices. Use appropriate personal protective equipment (PPE) including gloves, lab coat, and eye protection. Work in a well-ventilated area or fume hood when handling the neat liquid or concentrated solutions.
Storage recommendations for ester-amine compounds generally include cool, dry conditions away from strong oxidizers, strong acids, and moisture. The specific recommended storage temperature and shelf life for SKU E725556 are documented in the Aladdin Scientific product SDS and CoA. Customers are advised to check these documents upon receipt of the product.
Disposal: Dispose of this compound and its solutions in accordance with local institutional and governmental regulations for organic nitrogen-containing waste.
Purity, Grade, and Specifications
Aladdin Scientific supplies 1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester (E725556) as a research-grade reagent. The confirmed purity specification, analytical method (e.g., GC or HPLC), and lot-specific data are provided on the Certificate of Analysis (CoA) accompanying each shipment. Customers requiring a specific minimum purity for sensitive synthetic or biological applications should review the CoA before use or contact Aladdin Scientific technical support for guidance.
If a higher purity grade or custom quantity is required, please reach out to the Aladdin Scientific sales team to discuss custom synthesis or bulk procurement options.
Ordering and Availability
1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester is available for order from Aladdin Scientific under SKU E725556. To place an order, visit the Aladdin Scientific website, search by product name or SKU, and add the desired pack size to your cart. Institutional purchase orders, credit card payments, and other standard procurement channels are supported.
For questions about lead times, bulk pricing, export documentation, or availability in your region, please contact Aladdin Scientific customer service or your regional sales representative. Current stock levels and pricing are displayed in real time on the product page.
Common Research Applications
1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester serves primarily as a synthetic intermediate. The piperidine ring system is one of the most frequently encountered saturated nitrogen heterocycles in approved pharmaceuticals, and N-alkyl-piperidine-4-carboxylate esters are useful precursors for further functionalization. Typical transformations include hydrolysis of the ester to the corresponding carboxylic acid, reduction to the alcohol or aldehyde, amide coupling, and further N-alkylation or N-acylation reactions.
Researchers in medicinal chemistry, process chemistry, and materials science may employ this compound as a starting material or intermediate in the construction of more complex piperidine-containing target molecules. Specific published applications should be identified by the researcher through a literature search using Chemical Abstracts, SciFinder, or Reaxys.
Frequently asked questions
What is the CAS number or molecular formula of 1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester?
The molecular formula of 1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester is C10H19NO2, corresponding to an N-ethyl piperidine ring bearing an ethyl ester substituent at the 4-position. For the confirmed CAS number and full physicochemical data for SKU E725556, please refer to the Aladdin Scientific product page or the accompanying Certificate of Analysis, as lot-specific details are authoritative.
How should 1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester be stored to maintain stability?
General best practice for N-alkyl piperidine ester compounds is to store them in a tightly sealed container under cool, dry conditions, away from strong acids, oxidizers, and moisture. The specific storage temperature and recommended shelf life for E725556 are stated in the Aladdin Scientific SDS and CoA; always consult these documents for authoritative guidance.
What purity grade is available for E725556 from Aladdin Scientific?
E725556 is offered as a research-grade reagent by Aladdin Scientific. The exact purity percentage and the analytical method used to determine it are documented on the Certificate of Analysis (CoA) provided with each lot. If your application requires a specific minimum purity, please contact Aladdin Scientific technical support before placing your order.
Can 1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester be used directly in biological assays?
This compound is catalogued primarily as a synthetic intermediate rather than a validated biological probe or active pharmaceutical ingredient. Its suitability for direct biological assay use depends on the assay type, required purity, and solubility in the assay medium. Researchers should review the CoA, confirm purity meets their requirements, and consult relevant literature before use in biological experiments.
How do I place an order for E725556 and what payment methods are accepted?
You can order E725556 directly through the Aladdin Scientific website by searching for the SKU or product name and selecting your required pack size. Aladdin Scientific accepts institutional purchase orders, major credit cards, and other standard payment methods. For bulk orders or special pricing, contact the Aladdin Scientific sales team directly.
References
- Aladdin Scientific product page for 1-Ethyl-4-Piperidinecarboxylic Acid Ethyl Ester, SKU E725556.
- March, J. Advanced Organic Chemistry: Reactions, Mechanisms, and Structure, 4th ed.; Wiley-Interscience: New York, 1992. (General reference for ester and amine chemistry.)
- Lovering, F.; Bikker, J.; Humblet, C. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success. J. Med. Chem. 2009, 52, 6752–6756. (Context for piperidine ring importance in drug discovery.) doi:10.1021/jm901241e
Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
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