3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid: FAQs
3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid: FAQs
3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid is a benzochromene-based heterocyclic compound featuring a fused naphtho-pyranone scaffold with a carboxylic acid functionality at the 2-position, supplied by Aladdin Scientific (SKU O170357) for use in synthetic chemistry and research applications.
- Product Name
- 3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid
- SKU
- O170357
- Compound Class
- Benzochromene heterocyclic carboxylic acid
- Core Scaffold
- Fused naphtho-pyranone (benzo[f]chromene) ring system
- Key Functional Group
- Carboxylic acid at C-2 position; lactone carbonyl at C-3
- Supplier
- Aladdin Scientific
Chemical Identity and Structure
3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid belongs to the chromene family of oxygen-containing heterocyclic compounds. Its systematic name describes a benzo[f]chromene core—a tricyclic ring system formed by the fusion of a benzene ring with a naphthalene-based chromene (2H-pyran-2-one) scaffold. The compound carries a ketone (lactone) carbonyl at the 3-position and a free carboxylic acid group at the 2-position, making it a versatile building block for further synthetic elaboration.
The planar, aromatic-rich structure contributes to the compound's potential utility in medicinal chemistry and materials science research, where chromene and coumarin derivatives are widely investigated as privileged scaffolds.
Purity, Specifications, and Quality
Aladdin Scientific supplies 3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid (SKU O170357) as a research-grade reagent. Researchers are advised to consult the product page and the accompanying Certificate of Analysis (CoA) for the specific lot purity, analytical method (e.g., HPLC or NMR confirmation), and physical form at the time of purchase.
When evaluating suitability for a particular application, consider whether the stated purity meets the sensitivity requirements of your assay or synthetic route. For high-precision work, additional in-house characterisation such as LC-MS or 1H NMR may be warranted.
Storage and Handling Guidelines
As with most solid organic reagents containing a carboxylic acid and a lactone moiety, 3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid should be stored in a cool, dry environment away from moisture and direct light. A tightly sealed container is recommended to prevent hygroscopic uptake or photodegradation of the compound over time.
Standard laboratory personal protective equipment (PPE) — including gloves, safety glasses, and a laboratory coat — should be worn when handling this material. Refer to the Safety Data Sheet (SDS) available from Aladdin Scientific for comprehensive hazard information, first-aid measures, and disposal guidance before use.
Applications in Research
Chromene-2-carboxylic acid derivatives are recognised as useful intermediates in synthetic organic chemistry. The free carboxylic acid at C-2 enables straightforward coupling reactions—including amide bond formation, esterification, and decarboxylative functionalisations—to generate diverse analogues for structure-activity relationship (SAR) studies.
The benzo[f]chromene scaffold has been reported in the literature in the context of compounds with biological screening interest; however, researchers should conduct independent literature searches to identify the most current and relevant studies for their specific application. Aladdin Scientific makes no therapeutic claims for this research reagent.
Ordering and Customer Support
3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid can be ordered directly from Aladdin Scientific using SKU O170357. Bulk or custom quantities may be available; contact Aladdin Scientific's sales or technical support team for quotations, lead times, and availability information.
For questions about order status, invoicing, returns, or shipment tracking, please reach out to Aladdin Scientific customer service through the official website. The team can also provide guidance on SDS documents, CoA requests, and regulatory documentation required for import or institutional procurement.
Frequently asked questions
What is 3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid and what is its core structure?
3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid is a tricyclic heterocyclic compound built on a benzo[f]chromene scaffold, which consists of a fused benzene–naphtho–pyranone ring system. It bears a lactone carbonyl at C-3 and a free carboxylic acid at C-2, making it a reactive and versatile building block for synthetic chemistry.
How should 3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid be stored to maintain stability?
The compound should be stored in a tightly sealed container in a cool, dry location, away from moisture, heat, and direct light. These precautions help prevent hygroscopic degradation and photodegradation of the lactone and carboxylic acid functional groups. Always consult the product SDS for lot-specific storage recommendations.
What are the typical research applications of this compound?
The compound serves primarily as a synthetic intermediate in medicinal and organic chemistry. The carboxylic acid group at C-2 enables amide coupling, esterification, and decarboxylative reactions to generate structural analogues. The benzo[f]chromene scaffold is of interest to researchers conducting SAR studies on chromene-based compound libraries. No therapeutic claims are made by Aladdin Scientific for this reagent.
How can I obtain the Certificate of Analysis (CoA) or Safety Data Sheet (SDS) for SKU O170357?
The CoA and SDS for 3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid (SKU O170357) are available through the Aladdin Scientific official website. You can search by SKU or lot number to download the relevant documents, or contact Aladdin Scientific customer service directly to request them.
Is 3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid available in bulk or custom quantities?
Aladdin Scientific may be able to accommodate bulk or custom quantity requests for SKU O170357. Please contact the Aladdin Scientific sales team directly with your quantity requirements and timeline so they can provide a tailored quotation and confirm availability and lead times.
References
- Aladdin Scientific product page for 3-Oxo-3H-Benzo[f]Chromene-2-Carboxylic Acid, SKU O170357.
- General reference: March, J. Advanced Organic Chemistry: Reactions, Mechanisms, and Structure. Wiley, for context on carboxylic acid coupling reactions.
- General reference: Chromene and coumarin scaffolds in medicinal chemistry — textbook-level knowledge; specific literature citations for benzo[f]chromene biological activity should be verified independently.
Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
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