What Is 4,4'-Diamino-[1,1'-Biphenyl]-3,3'-Dicarboxylic Acid?

4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid is an aromatic bifunctional compound built on a biphenyl (two phenyl rings connected by a single bond) core. The molecule carries a primary amine (-NH₂) substituent and a carboxylic acid (-COOH) substituent on each of the two phenyl rings, positioned at the 4,4'- and 3,3'- sites respectively.

This combination of complementary reactive groups — nucleophilic amines and electrophilic/condensable carboxylic acids — on a rigid, planar aromatic scaffold gives the compound broad utility as a bifunctional monomer in condensation polymerization and as a multidentate ligand in coordination chemistry.

Aladdin Scientific supplies this compound under SKU D693620.

Key Properties and Handling

Physical state: 4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid is typically a solid powder at room temperature. Its exact melting point and solubility data should be confirmed from the product specification sheet provided by Aladdin Scientific.

Solubility: As a zwitterionic-capable species (containing both acidic and basic groups), solubility is expected to be moderate in polar aprotic solvents such as DMSO and DMF, and limited in nonpolar solvents. Dissolution may be aided by adjustment of pH or use of dilute aqueous base.

Storage: Store in a tightly sealed container, away from moisture, heat, and light. Keep under inert atmosphere conditions if long-term storage is required, to prevent oxidation of the amine groups.

Safety: Handle with standard laboratory precautions — wear appropriate PPE including gloves, lab coat, and eye protection. Consult the Safety Data Sheet (SDS) for detailed hazard information before use.

Applications in Research

The dual amine and dual carboxylic acid functionality of this compound makes it attractive for several research domains:

• Polyimide and polybenzimidazole synthesis: The amine groups can react with dianhydrides or aldehydes to form high-performance polymers used in membranes, coatings, and aerospace materials.
• Metal-Organic Frameworks (MOFs): The carboxylate groups coordinate to metal nodes while the amine groups can be further functionalized or participate in hydrogen bonding, enabling the design of porous materials for gas storage, separation, and catalysis.
• Covalent Organic Frameworks (COFs): Amine groups react with aldehydes via Schiff-base condensation to build crystalline porous networks.
• Pharmaceutical and dye intermediates: The biphenyl diamine motif is relevant to the synthesis of azo dyes and biologically active scaffolds.

Specific reaction conditions and yields will depend on the intended application; researchers should consult primary literature for detailed protocols.

Ordering and Quality Information

How to order: 4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid is available from Aladdin Scientific under SKU D693620. Orders can be placed through the Aladdin Scientific website or by contacting your regional sales representative.

Purity and grade: For exact purity specifications, batch-specific certificates of analysis (CoA), and available pack sizes, please refer to the current product listing on the Aladdin Scientific website or request documentation directly from Aladdin Scientific customer service.

Bulk and custom quantities: If you require larger quantities or custom packaging, contact Aladdin Scientific's sales team to discuss options and pricing.