l. Erythrocyte and hemoglobin depression is less severe than in acute granulomas, and juvenile erythrocytes are rare.

2. The white blood cell count is elevated in most cases, up to 10-30×109/L or more, but may be normal or decreased.

This experiment is from Mudanjiang Medical College, undergraduate 5-year laboratory guide for testing majors.

Operation method

Analysis of bone marrow picture of acute lymphatic leukemia and experimental characterization of each subtype

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Hematology:

l. Erythrocyte and hemoglobin depression is less severe than in acute granulomas, and juvenile erythrocytes are rare.

2. The white blood cell count is increased in most cases, up to 10-30×109/L or more, but there are also normal or decreased cases.

3. peripheral blood is dominated by primitive and naïve lymphocytes, which can account for 10-90%, such cells are easy to break, so more blue cells can be seen in the blood film, and neutrophils are extremely reduced or absent.

4. 80% of the cases in the early stage of the disease thrombocytopenia in half of the cases below 50 × 109 / L.

Bone marrow: myeloproliferative activity is extreme or obviously active, a few cases show active hyperplasia, with primitive and naive lymphocytes predominantly accounting for 50-90% of the cases. Accompanied by morphological abnormalities, such as irregular nuclear morphology, there may be depression, incision, folding and cleavage, nuclear chromatin is mud-like or coffee-colored granular, large nucleoli, cytoplasmic vacuoles, these cells are called Rieders-type primitive lymphocytes, mature lymphocytes are rare, the proliferation of granulocyte system is inhibited, granulocytes are reduced, or even rare, erythrocyte system proliferation is also inhibited, rare or not seen, megakaryocytes are also inhibited, most of them are significantly reduced or not seen, platelets are reduced or not seen. Most of the megakaryocyte lineage is significantly reduced or absent, platelets are reduced, degenerate cells are significantly increased, and blue cells (smear cells) are common.

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