The animal model of liver fire inflammation evidence refers to the animals with eye redness and swelling pain, headache, deafness and tinnitus, irritability, dryness and bitterness of the mouth, stools and urine yellow and short, red tongue, pale and dry, and number of strings in the pulse and other signs and symptoms. At present, the establishment of the animal model of liver fire inflammation evidence for acute iridocyclitis model alternative method.

Principle

The basic principle of the animal model of liver-fire upflaming syndrome is to use the animal model of acute iridocyclitis instead of the model of liver-fire upflaming syndrome based on the fact that its pathological changes are similar to those of human liver-fire upflaming syndrome.

Appliance

The animal model of Liver Fire Upper Inflammatory Symptom can be used for the study of Liver Fire Upper Inflammatory Symptom and the study of related prescription drugs.

Operation method

Reproduction of an animal model of liver-fire-upper-inflammation syndrome by substitution method in acute iridocyclitis model

Principle

The basic principle of the acute iridocyclitis model substitution method uses endotoxin to establish an animal model of acute iridocyclitis, which replaces the model of liver-fire upflaming evidence due to the similarity of their clinical manifestations and pathological changes.

Materials and Instruments

Laboratory animals:
① Male Japanese big-eared white rabbit.
Modeling drugs:
① Escherichia coli endotoxin.

Move

Acute iridocyclitis model alternative method to replicate the animal model of liver fire upflaming evidence was modeled as follows:
A. Model group animals were injected subcutaneously with endotoxin solution into the fleshy pads of both hind feet, 0.5 mL per animal.

Caveat

1. Pay attention to the immobilization of the rabbit.

2. When injecting the modeling drug, the technique should be gentle.

3. After injection, gently press the needle hole with a sterile cotton swab to prevent leakage of the drug.

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