Fractures and bone defects are the focus and difficulty of treatment in orthopaedics, and their repair process is affected by a variety of factors, while the long bone has the highest incidence of fracture, and the operation of the factors affecting the operation is simpler than that of its irregular and flat bones, so the development of models of fractures and bone defects of the long bone has been relatively mature, and there are a lot of research verified models such as the mouse bone fracture and defect model, the rabbit flexure bone fracture and defect model, and goat femur defect model, and so on. The classical models have been validated by a lot of researches. However, along with the emergence of new biomaterials and new techniques and theories, more considerations on the mechanics of fracture fixation have been reflected in the new models. The rise of tissue engineering has also revolutionized the repair of bone and nerve defects (including the spinal cord), and a large number of bone and nerve defect models have become more quantitative and standardized.

Principle

The basic principle of [Skeletal System Animal Model]: In recent years, it has been found that mechanical stimulation can stimulate osteoblasts to form bone and accelerate fracture healing, so the biological stress at the broken end of the fracture plays an important role in fracture healing, and elastic fixation Fangwu has appeared in the animal model and clinical practice, and the elastic fixation animal model can be used to observe and evaluate the way of healing of fracture breaks and the molecular mechanism under the stress, and provide a model for the development of new fixation concepts and fixation consumables. The animal model of elastic fixation can be used to observe and evaluate the healing mode and molecular mechanism of fracture breaks under stress, and provide a model for adapting to the development of new fixation concept and fixation consumables.

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