Cyclocarboxypropyloleic Acid: FAQs for Researchers
Cyclocarboxypropyloleic Acid: FAQs for Researchers
Cyclocarboxypropyloleic acid is a cyclopropane-ring-containing fatty acid derivative of oleic acid that has attracted research interest for its unique structural and biochemical properties.
- Chemical Class
- Cyclopropane fatty acid derivative (oleic acid-based)
- SKU
- C1022915
- Supplier
- Aladdin Scientific
- Primary Research Use
- Lipid biochemistry and membrane studies
- Storage Recommendation
- Store under inert atmosphere, away from light and moisture; consult SDS for specific temperature requirements
- Physical Form
- Typically a liquid or low-melting solid (verify with product specification sheet)
What Is Cyclocarboxypropyloleic Acid?
Cyclocarboxypropyloleic acid is a structural analogue of oleic acid (C18:1) in which a cyclopropane ring and an additional carboxylic acid functionality have been incorporated into or appended to the fatty acid backbone. This modification introduces conformational rigidity into the acyl chain, distinguishing it from straight-chain unsaturated fatty acids.
The compound belongs to the broader family of cyclopropane fatty acids (CPFAs), which are known to occur naturally in certain bacteria and plants. Synthetic or semi-synthetic variants such as cyclocarboxypropyloleic acid are used as research tools to probe membrane biophysics, enzyme substrate specificity, and lipid–protein interactions.
Note: Specific structural details (exact ring position, stereochemistry, molecular formula, and molecular weight) should be confirmed from the certificate of analysis (CoA) and safety data sheet (SDS) provided with SKU C1022915.
Properties, Solubility, and Handling
Physical properties: Like many fatty acid derivatives, cyclocarboxypropyloleic acid is expected to be a viscous liquid or low-melting solid at room temperature. Exact melting point, boiling point, and density values should be obtained from the product specification sheet for SKU C1022915.
Solubility: As a lipophilic compound with one or more carboxylic acid groups, it is expected to dissolve readily in common organic solvents such as ethanol, methanol, chloroform, and DMSO. Aqueous solubility is likely limited without the use of solubilizing agents (e.g., cyclodextrins, albumin conjugation, or alkaline conditions to form the carboxylate salt). Always verify solubility experimentally before use in biological assays.
Handling precautions: Handle under inert gas (nitrogen or argon) to minimise oxidation of the fatty acid chain. Avoid prolonged exposure to light, heat, and atmospheric moisture. Wear appropriate PPE (gloves, lab coat, eye protection) and consult the SDS for hazard classification and first-aid measures.
Storage and Stability
Fatty acid derivatives are susceptible to autoxidation, hydrolysis, and photodegradation. To maximise shelf life of cyclocarboxypropyloleic acid (SKU C1022915):
- Store in a tightly sealed container under inert atmosphere (nitrogen or argon).
- Keep away from direct light; amber vials or aluminium foil wrapping are recommended.
- Follow the temperature recommendation on the product label or CoA (commonly −20 °C for long-term storage of lipid standards).
- Aliquot into single-use volumes to avoid repeated freeze–thaw cycles.
- Monitor the compound for discolouration or turbidity as indicators of degradation before use.
Specific stability data and expiry information are provided on the CoA accompanying each lot of SKU C1022915.
Research Applications
Cyclocarboxypropyloleic acid and related cyclopropane fatty acids have been explored in several research contexts:
- Membrane biophysics: Cyclopropane rings reduce conformational flexibility of acyl chains, affecting membrane fluidity and phase behaviour. The compound can be used as a probe or standard in such studies.
- Enzyme substrate studies: Investigating the substrate specificity of lipases, phospholipases, and fatty acid-metabolising enzymes toward structurally constrained fatty acids.
- Lipid standards and analytics: As a structurally defined fatty acid derivative, it may serve as an analytical standard in GC, LC-MS, or NMR-based lipidomics workflows.
- Antimicrobial and stress-response research: Bacterial cyclopropane fatty acids are associated with stress adaptation; synthetic analogues assist mechanistic studies.
Researchers should validate the suitability of SKU C1022915 for their specific application and consult primary literature for experimental precedents.
Ordering, Documentation, and Support
How to order: Cyclocarboxypropyloleic acid is available from Aladdin Scientific under SKU C1022915. Place orders via the Aladdin Scientific website, by email, or through authorised distributors in your region.
Documentation available: Each shipment is accompanied by a Certificate of Analysis (CoA) stating purity, lot number, and characterisation data. Safety Data Sheets (SDS) are available for download on the product page. Contact Aladdin Scientific customer support to request additional technical documents.
Technical support: For application-specific questions, handling advice, or bulk/custom quantity enquiries, contact the Aladdin Scientific technical support team via the website contact form or customer service email.
Frequently asked questions
What is the molecular structure of cyclocarboxypropyloleic acid?
Cyclocarboxypropyloleic acid is a fatty acid derivative based on oleic acid (C18:1) that incorporates a cyclopropane ring and an additional carboxypropyl or carboxylic acid group. The exact molecular formula, molecular weight, and ring position should be confirmed from the Certificate of Analysis (CoA) for SKU C1022915, as structural details can vary between synthetic preparations.
In what solvents can cyclocarboxypropyloleic acid be dissolved?
As a lipophilic fatty acid derivative, cyclocarboxypropyloleic acid is generally expected to dissolve well in organic solvents such as ethanol, methanol, chloroform, and DMSO. Aqueous dissolution is limited without the aid of solubilising agents such as albumin, cyclodextrins, or alkaline pH to form the carboxylate salt. Researchers should verify solubility experimentally for their specific buffer or assay conditions.
How should cyclocarboxypropyloleic acid (SKU C1022915) be stored to maintain stability?
Store the compound in a tightly sealed container under an inert atmosphere (nitrogen or argon), protected from light and moisture. Long-term storage at −20 °C is generally recommended for lipid standards. Aliquoting into single-use portions minimises degradation from repeated freeze–thaw cycles. Always refer to the CoA and SDS supplied with each lot for lot-specific storage guidance.
What are the typical research applications of cyclocarboxypropyloleic acid?
The compound is used in research areas including membrane biophysics (studying the effect of conformationally constrained acyl chains on membrane properties), enzyme substrate specificity studies, lipidomics as an analytical standard, and mechanistic research into bacterial stress-response pathways involving cyclopropane fatty acids. Validate its suitability for your specific experimental system before use.
How can I obtain the Certificate of Analysis or Safety Data Sheet for SKU C1022915?
The Certificate of Analysis (CoA) is included with each shipment of SKU C1022915 and can also be requested from Aladdin Scientific customer support by providing your lot number. The Safety Data Sheet (SDS) is available for download directly from the product page on the Aladdin Scientific website.
References
- General reference: Bacterial cyclopropane fatty acids and their biological roles — textbook-level knowledge; no specific paper cited.
- Aladdin Scientific product page for Cyclocarboxypropyloleic acid, SKU C1022915. Aladdin Scientific.
Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
危险品化学品经营许可证(带存储)