常见问题(FAQs)

EDTA Lead(II) Disodium Salt Hydrate: FAQs & Lab Guide

Ethylenediaminetetraacetic Acid Lead(II) Disodium Salt Hydrate is a well-defined lead–EDTA coordination complex supplied as a water-soluble crystalline solid, widely used as a reference standard and reagent in analytical chemistry, environmental testing, and chelation research.

Product Name
Ethylenediaminetetraacetic Acid Lead(II) Disodium Salt Hydrate
SKU
E156499
Chemical Class
Metal–EDTA chelate complex (Pb²⁺ coordinated by EDTA tetradentate ligand, disodium salt form)
Physical Form
Crystalline solid (hydrate)
Solubility
Soluble in water; insoluble in most common organic solvents
Key Application
Analytical reference standard, chelation studies, environmental lead analysis
Hazard Classification
Contains lead; handle as toxic heavy metal reagent in accordance with local regulations

What Is Ethylenediaminetetraacetic Acid Lead(II) Disodium Salt Hydrate?

Ethylenediaminetetraacetic Acid Lead(II) Disodium Salt Hydrate (SKU E156499) is the disodium salt of the 1:1 chelate complex formed between lead(II) ions (Pb²⁺) and ethylenediaminetetraacetic acid (EDTA). In this complex, the hexadentate EDTA ligand coordinates to Pb²⁺ through its four carboxylate oxygen atoms and two amine nitrogen atoms, forming a highly stable, water-soluble coordination compound.

The compound is supplied as a crystalline hydrate, meaning a defined number of water molecules are incorporated into the crystal lattice. The disodium salt form ensures good aqueous solubility, making it convenient for preparation of standard solutions in analytical workflows. It is catalogued at Aladdin Scientific under SKU E156499.

Typical Applications and Uses in Research

This compound finds use across several research and analytical domains:

  • Analytical Reference Standards: As a chemically defined, stable source of complexed lead, it is used to prepare calibration standards for atomic absorption spectrometry (AAS), inductively coupled plasma mass spectrometry (ICP-MS), and other trace metal analytical techniques.
  • Chelation Chemistry Research: The compound serves as a model system for studying metal–ligand interactions, stability constants, and ligand exchange kinetics involving EDTA and divalent heavy metals.
  • Environmental and Biological Studies: Researchers investigating lead speciation, bioavailability, or detoxification pathways may use the EDTA-chelated form as a controlled lead source to distinguish free ion effects from complexed lead effects.
  • Method Development and Validation: Laboratories developing or validating methods for lead determination in water, soil extracts, or biological matrices may use this compound as a spiking reagent or matrix-matched standard.

Researchers should confirm suitability for their specific application, as some assays require free Pb²⁺ rather than the chelated form.

Storage, Handling, and Safety Considerations

Storage: Store the compound in a tightly sealed container in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and strong oxidizers. As a hydrate, exposure to excessive heat or vacuum desiccation conditions may alter the water content and thus the effective concentration of solutions prepared from it. Consult the product's Safety Data Sheet (SDS) for specific storage temperature recommendations.

Handling: Because the compound contains lead, it must be handled with appropriate personal protective equipment (PPE) including nitrile gloves, safety glasses, and a laboratory coat. Work in a well-ventilated area or under a fume hood when handling powders to avoid inhalation of dust. Avoid ingestion and skin contact.

Waste Disposal: Lead-containing waste must be disposed of in accordance with national and local hazardous waste regulations. Do not pour lead-containing solutions down the drain without appropriate treatment or authorization. Consult your institution's Environmental Health and Safety (EHS) office for guidance.

Regulatory Status: Lead and its compounds are subject to regulation under frameworks such as REACH (EU), RoHS, and various national occupational exposure limit standards. Users are responsible for compliance with applicable regulations in their jurisdiction.

Purity, Specification, and Quality Assurance

Aladdin Scientific supplies Ethylenediaminetetraacetic Acid Lead(II) Disodium Salt Hydrate (E156499) as a research-grade reagent. Specific purity values, lot-specific certificates of analysis (CoA), and analytical test data are available on the product page or upon request from technical support.

When evaluating the compound for use as a quantitative analytical standard, researchers should pay attention to:

  • Assay (purity): The percentage of the active chelate complex on a dry or as-is basis.
  • Water content: For a hydrate, knowing the precise degree of hydration is important when calculating molar concentrations. Karl Fischer titration is a common method for determining water content.
  • Heavy metal impurities: For applications requiring high purity, verify that the CoA includes data on trace metal impurities.
  • Lot-to-lot consistency: Request CoA for the specific lot received to confirm specifications are met.

Contact Aladdin Scientific technical support for the most current specification sheet and CoA for SKU E156499.

Ordering, Availability, and Technical Support

How to Order: Ethylenediaminetetraacetic Acid Lead(II) Disodium Salt Hydrate is available from Aladdin Scientific under SKU E156499. Orders can be placed through the Aladdin Scientific website, by contacting your regional sales representative, or through authorized distributors. Procurement teams should reference the SKU to ensure correct product selection.

Packaging and Quantities: Available pack sizes are listed on the product page. Contact sales for bulk quantity inquiries or custom packaging requirements.

Technical Support: For application-specific guidance, compatibility questions, or specification inquiries, contact Aladdin Scientific technical support. Certificate of Analysis (CoA) documents for specific lots can be downloaded from the website using the lot number or requested from customer service.

Export Controls and Import Regulations: Lead compounds may be subject to export controls or import restrictions in certain countries. Buyers are responsible for verifying regulatory compliance for international shipments.

Frequently asked questions

What is the difference between free lead(II) nitrate and EDTA Lead(II) Disodium Salt Hydrate for analytical use?

Free lead salts such as lead(II) nitrate dissociate in solution to release hydrated Pb²⁺ ions, which are the species detected in most direct metal assays. EDTA Lead(II) Disodium Salt Hydrate provides lead in a strongly chelated, complexed form with a high stability constant, meaning very little free Pb²⁺ is present in solution. Researchers should select the form appropriate to their assay: use the free salt where free ion activity is required, and the chelated form where a stable, well-defined lead complex is needed for speciation or method validation studies.

How should I prepare a standard solution from EDTA Lead(II) Disodium Salt Hydrate?

Accurately weigh the required amount of compound using a calibrated analytical balance, accounting for the water of hydration in your molar mass calculation (confirm the exact degree of hydration from the product's Certificate of Analysis). Dissolve in high-purity water (e.g., ASTM Type I or equivalent) and dilute to the desired volume in a volumetric flask. Prepare solutions fresh or verify stability under your storage conditions, and store in clean, lead-free containers. Acidification (e.g., trace-metal-grade nitric acid) may be required for very dilute solutions to prevent adsorption losses, but note that strong acid may disrupt the EDTA chelate; verify conditions for your specific application.

Is EDTA Lead(II) Disodium Salt Hydrate (E156499) classified as a hazardous material for shipping?

Lead compounds are generally classified as environmentally hazardous substances and may be subject to special packaging, labeling, and documentation requirements under IATA, IMDG, and DOT transport regulations. The exact classification depends on the quantity shipped, physical form, and applicable transport mode. Aladdin Scientific follows applicable regulations for packaging and shipping; customers should review the product SDS and contact Aladdin Scientific customer service or their freight carrier for guidance on import/export and transport requirements specific to their location.

What personal protective equipment (PPE) is recommended when handling this compound?

At minimum, wear chemical-resistant gloves (nitrile recommended), safety glasses or goggles, and a laboratory coat when handling Ethylenediaminetetraacetic Acid Lead(II) Disodium Salt Hydrate. When working with powders or generating aerosols, use a fume hood or local exhaust ventilation and consider a dust/particulate respirator if ventilation controls are insufficient. Always consult the product Safety Data Sheet (SDS) for complete hazard information and PPE recommendations before use.

How stable is EDTA Lead(II) Disodium Salt Hydrate in aqueous solution over time?

EDTA–metal chelates are generally considered stable in aqueous solution over extended periods when stored properly; however, stability can be influenced by pH, temperature, exposure to competing metal ions, and microbial growth. For critical quantitative applications, it is recommended to prepare solutions freshly, store them in tightly sealed, lead-free containers at low temperature, and validate solution stability under your specific laboratory conditions. Specific shelf-life data for prepared solutions are not provided in available source material and should be verified experimentally or confirmed with Aladdin Scientific technical support.

References

  1. Martell, A.E.; Smith, R.M. Critical Stability Constants. Plenum Press, New York. (General reference for EDTA–metal stability constants including Pb–EDTA.)
  2. Cotton, F.A.; Wilkinson, G.; Murillo, C.A.; Bochmann, M. Advanced Inorganic Chemistry, 6th ed. Wiley-Interscience. (Textbook-level reference for EDTA coordination chemistry.)
  3. Aladdin Scientific Product Page: Ethylenediaminetetraacetic Acid Lead(II) Disodium Salt Hydrate, SKU E156499. Aladdin Scientific.

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.

目录: 常见问题(FAQs)

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产品仅供科研与开发使用,不用于人体、动物、诊断或治疗。

引用本文

阿拉丁科学.《EDTA Lead(II) Disodium Salt Hydrate: FAQs & Lab Guide》. 阿拉丁知识库,更新于 2026年10月23日。 https://www.aladdin-e.com/zh_cn/faqs/edta-lead-ii-disodium-salt-hydrate-faq-en.html
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