What Is This Compound and What Is It Used For?

1,5-Bis(1,1-dimethylethyl) N-((((1S)-5-amino-1-((1,1-dimethylethoxy)carbonyl)pentyl)amino)carbonyl)-L-glutamate (Aladdin SKU: B1046896) is a synthetic, orthogonally protected dipeptide-type building block. The molecule combines an L-glutamate residue bearing two tert-butyl ester protecting groups with a lysine-derived fragment connected through a urea or carbamate-type carbonyl linkage. A free primary amine is retained at the terminal position of the lysine-derived chain, providing a reactive handle for further chemical elaboration.

This structural profile makes the compound useful as an intermediate or building block in peptide chemistry, combinatorial library synthesis, and bioconjugation workflows where selective deprotection of the tert-butyl esters under mild acidic conditions (e.g., trifluoroacetic acid) is required. Researchers in medicinal chemistry and chemical biology may employ such building blocks for the construction of peptidomimetics or bifunctional linkers.

How Should This Compound Be Stored and Handled?

As with most protected amino acid and dipeptide building blocks, proper storage is essential to maintain chemical integrity. General best-practice guidelines apply in the absence of specific stability data supplied with your lot:

• Temperature: Store at 2–8 °C (refrigerator) or as indicated on the product label and Certificate of Analysis (CoA). For long-term archiving, storage at −20 °C under inert atmosphere is commonly recommended for sensitive protected amino acid derivatives.
• Atmosphere: Protect from moisture and oxygen. Store under nitrogen or argon where possible, especially after the container has been opened.
• Light: Keep away from direct light to prevent potential photodegradation.
• Handling: Use standard personal protective equipment (gloves, lab coat, eye protection). Consult the Safety Data Sheet (SDS) for this product before use.

Always verify storage conditions against the CoA provided with your specific lot, as empirical stability data for the exact batch takes precedence over general guidance.

How Do I Verify Purity and Identity Upon Receipt?

Aladdin Scientific provides a Certificate of Analysis (CoA) with each shipment. The CoA documents the analytical characterization performed on the specific lot and typically includes:

• Identity confirmation: Techniques such as NMR spectroscopy (¹H and/or ¹³C) and high-resolution mass spectrometry (HRMS or LC-MS) are standard for confirming the molecular structure of compounds such as B1046896.
• Purity assessment: HPLC purity (area percent) is the most common metric reported for synthetic building blocks of this type.
• Appearance: Visual description (e.g., white to off-white solid or oil).

If you require additional characterization data beyond what is provided on the CoA, or if your in-house analysis reveals a discrepancy, please contact Aladdin Scientific technical support promptly and retain the original packaging for reference. Independent verification by LC-MS or ¹H NMR in a deuterated solvent appropriate for this compound (e.g., CDCl₃ or DMSO-d₆) is recommended as a routine in-lab check.

Ordering, Availability, and Custom Quantities

B1046896 is listed in the Aladdin Scientific catalog. To place an order or inquire about availability:

• Visit the Aladdin Scientific website and search by SKU B1046896 or by the IUPAC name to locate the product page with current stock status and pricing.
• Standard pack sizes are shown on the product page. If your project requires a quantity not listed, contact Aladdin's sales team to discuss custom synthesis or bulk sourcing options.
• For institutional or high-volume orders, procurement managers should contact Aladdin Scientific directly for volume pricing and lead-time information.

When placing your order, ensure the purchase order references the exact SKU (B1046896) and the desired quantity and pack size to avoid fulfillment errors.