This experiment is from the official website of the Fourth Military Medical University

Operation method

Morphologic observation experiments on acute common hepatitis

Materials and Instruments

Gross specimen Tissue section

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1. The lesions consist of extensive hepatocellular degeneration with slight necrosis in a punctate distribution.

2. Hepatocellular edema: the hepatocytes are enlarged and rounded, the cytoplasm becomes hollow and translucent, and some cells are 3 to 4 times larger than normal, which is called balloon-like change. Hepatocyte cords are disorganized and hepatic sinusoids are narrowed due to the enlargement of hepatocytes.

3. Eosinophilic hepatocytes: individual hepatocytes are eosinophilic with deep red coloration of the cytoplasm. In severe cases, the nucleus disappears and becomes a round deep red body, i.e. acidophilic body.

4. a few pitting necrotic areas scattered distribution, only 1 to several hepatocytes involved, necrotic hepatocytes have disappeared, and replaced by lymphocytes and phagocytes.

Caveat

Diagnostic points:1. extensive hydropic degeneration of hepatocytes;2. punctate necrosis;3. little inflammatory cell infiltration

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