What Is NSP-AS?

NSP-AS is a small-molecule tool compound supplied by Aladdin Scientific under SKU N649298. It is cross-referenced with the MedChemExpress catalogue number HY-D0891, allowing researchers to correlate data across supplier databases. Tool compounds such as NSP-AS are designed to interrogate specific biological targets or pathways, enabling mechanistic studies in cell-based and biochemical assay systems.

As a research-grade reagent, NSP-AS is intended for in vitro and preclinical research purposes only and is not approved for human therapeutic or diagnostic use. Researchers should consult the product's Safety Data Sheet (SDS) and Certificate of Analysis (CoA) prior to use.

Key Physicochemical Properties

Detailed physicochemical data for NSP-AS—including molecular weight, molecular formula, purity, solubility profile, and melting point—are provided in the product's Certificate of Analysis (CoA) and technical datasheet available on the Aladdin Scientific website. Researchers are advised to retrieve the batch-specific CoA at the time of purchase to confirm purity and specification.

General best practices for small-molecule reagents of this class include:

• Preparing stock solutions in anhydrous DMSO (typically 10–50 mM) and storing aliquots at −20 °C or below to prevent repeated freeze–thaw degradation.
• Verifying solubility in the target assay buffer before use, as aqueous solubility can vary significantly between compound classes.
• Protecting solutions from prolonged light exposure if the compound bears light-sensitive functional groups.

Research Applications

NSP-AS (HY-D0891) is positioned as a chemical biology tool compound. Typical research contexts for compounds in this classification include:

• Target engagement assays: Confirming that the compound binds to its intended molecular target using techniques such as thermal shift assay (TSA/DSF), surface plasmon resonance (SPR), or isothermal titration calorimetry (ITC).
• Cellular pathway modulation studies: Evaluating phenotypic and molecular responses in cell lines following compound treatment, often in conjunction with relevant reporter assays or proteomics workflows.
• Structure–activity relationship (SAR) programs: Serving as a reference or benchmark compound when profiling analogues within a medicinal chemistry campaign.

Researchers requiring specific mechanistic data on NSP-AS should consult the primary literature associated with HY-D0891 and verify applicability to their experimental system.

Safe Handling & Storage Recommendations

All handling of NSP-AS should be conducted in accordance with standard laboratory safety practices for research chemicals:

• Wear appropriate personal protective equipment (PPE), including nitrile gloves, lab coat, and safety glasses.
• Work in a well-ventilated area or fume hood when weighing powders or preparing concentrated solutions.
• Consult the product SDS for specific hazard classifications, first-aid measures, and disposal requirements before beginning work.
• Store the compound under the conditions specified on the product label and CoA. Many small-molecule reagents are best stored desiccated at −20 °C and protected from light.
• Do not use NSP-AS beyond its stated expiry date; re-verify purity by analytical methods (e.g., HPLC, NMR) if long-term storage has occurred.

For queries regarding hazard classification or regulatory compliance, contact Aladdin Scientific's technical support team.

Ordering & Technical Support

NSP-AS is available for direct purchase from Aladdin Scientific using SKU N649298. To place an order or request a formal quotation:

• Visit the Aladdin Scientific website and search by SKU N649298 or product name NSP-AS.
• Contact your regional Aladdin Scientific sales representative for volume pricing, custom packaging, or expedited shipping options.
• Request a batch-specific Certificate of Analysis (CoA) and Safety Data Sheet (SDS) at the time of ordering.

For technical questions about experimental application, solubility optimization, or assay compatibility, please reach out to the Aladdin Scientific technical support team. Our specialists can help ensure that NSP-AS is deployed effectively within your research workflow.