PITRM1 Mouse mAb: Key Facts, Usage & FAQs
PITRM1 Mouse mAb: Key Facts, Usage & FAQs
PITRM1 Mouse mAb is a mouse-derived monoclonal antibody targeting PITRM1 (pitrilysin metallopeptidase 1), supplied by Aladdin Scientific (SKU Ab350632) in a PBS-only formulation for research use.
- Product Name
- PITRM1 Mouse mAb
- SKU
- Ab350632
- Antibody Type
- Mouse Monoclonal Antibody (mAb)
- Formulation
- PBS only
- Target Protein
- PITRM1 (Pitrilysin Metallopeptidase 1)
- Supplier Reference
- absea KC-3903
What Is PITRM1 and Why Is It a Research Target?
PITRM1 (Pitrilysin Metallopeptidase 1) is a mitochondrial metalloprotease belonging to the pitrilysin subfamily of zinc-dependent endopeptidases. It is involved in the degradation of mitochondrial targeting sequences after they are cleaved from imported preproteins, and has been studied in the context of mitochondrial protein quality control. Research has also implicated PITRM1 in the clearance of amyloid beta peptides within mitochondria, making it of interest in neurodegeneration research. Loss-of-function variants in PITRM1 have been associated with progressive neurodegenerative conditions in human genetic studies.
Product Specifications and Formulation
Aladdin Scientific's PITRM1 Mouse mAb (SKU: Ab350632) is a mouse-derived monoclonal antibody supplied in a PBS-only formulation. The internal reference for this clone is absea KC-3903. As a PBS-only formulation, the antibody does not contain stabilizing proteins such as BSA or glycerol unless otherwise specified; researchers should verify the exact buffer composition on the product datasheet before use. It is recommended to aliquot the antibody upon first thaw to minimize freeze-thaw cycles and maintain activity.
Recommended Storage and Handling
For long-term storage, monoclonal antibodies in PBS-only formulations are generally recommended to be stored at -20°C or -80°C. Repeated freeze-thaw cycles should be avoided as they may reduce antibody integrity and binding performance. Once thawed, working aliquots may be kept at 4°C for short-term use. Avoid prolonged exposure to light and keep the antibody on ice during experimental setup. Always consult the official Aladdin Scientific product datasheet for Ab350632 for confirmed storage conditions specific to this product.
Ordering and Availability
PITRM1 Mouse mAb is available from Aladdin Scientific under SKU Ab350632. To place an order, customers may visit the Aladdin Scientific website, contact their regional sales representative, or reach out to customer service. For bulk quantities, custom conjugation, or institutional pricing inquiries, please contact Aladdin Scientific's sales team directly. Ensure that purchase orders reference SKU Ab350632 and the internal clone reference absea KC-3903 to avoid confusion with other anti-PITRM1 products.
Frequently asked questions
What is the formulation of PITRM1 Mouse mAb (Ab350632)?
PITRM1 Mouse mAb (Ab350632) is supplied in a PBS-only formulation. It does not contain added stabilizers such as BSA or glycerol unless specified on the product datasheet. Researchers should consult the official datasheet for complete buffer composition details.
What applications is PITRM1 Mouse mAb validated for?
Specific validated applications for Ab350632 are not listed in the current source material. Common applications for mouse monoclonal antibodies include Western blot (WB), immunofluorescence (IF), immunoprecipitation (IP), and ELISA. Please refer to the official Aladdin Scientific product datasheet for confirmed application data.
How should PITRM1 Mouse mAb be stored to maintain optimal activity?
For long-term storage, it is generally recommended to keep PBS-formulated monoclonal antibodies at -20°C or -80°C in single-use aliquots to avoid repeated freeze-thaw cycles. Short-term storage at 4°C is acceptable for working aliquots. Always confirm storage conditions from the product datasheet for Ab350632.
What species does the PITRM1 Mouse mAb target, and what is its host species?
This antibody is a mouse monoclonal antibody (mAb), meaning it was raised in a mouse host. The specific target species reactivity (e.g., human, mouse, rat) is not detailed in the available source material; please consult the Ab350632 product datasheet on the Aladdin Scientific website for confirmed reactivity information.
How can I order PITRM1 Mouse mAb from Aladdin Scientific?
You can order PITRM1 Mouse mAb (Ab350632) directly through the Aladdin Scientific website or by contacting your regional Aladdin Scientific sales representative. Reference SKU Ab350632 and clone reference absea KC-3903 when placing your order to ensure accuracy.
References
- Aladdin Scientific product page for PITRM1 Mouse mAb, SKU Ab350632. Internal clone reference: absea KC-3903.
Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
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