Product Overview: What Is HSP90AA4P?

HSP90AA4P is a human pseudogene locus belonging to the HSP90 (Heat Shock Protein 90) alpha family. Pseudogenes are genomic sequences that structurally resemble functional genes but have historically been considered non-coding. Emerging research indicates that some pseudogenes may produce transcripts or protein products with regulatory or functional significance in cellular stress responses.

Recombinant Human HSP90AA4P Protein (SKU: rp373251) is produced to enable researchers to explore the potential molecular roles of this pseudogene-derived sequence. The product is offered for research use only and is not intended for clinical, diagnostic, or therapeutic applications.

Expression, Purity, and Quality

Recombinant proteins in the HSP90 family are typically expressed in heterologous systems such as Escherichia coli, insect cells (baculovirus), or mammalian cell lines, depending on the requirement for post-translational modifications. Specific expression host, tag information, and purity grade for rp373251 should be confirmed with Aladdin Scientific technical support or the accompanying product datasheet, as detailed specifications were not included in the current source material.

Quality control for recombinant proteins generally includes SDS-PAGE analysis to confirm molecular weight and purity, as well as endotoxin testing for applications sensitive to lipopolysaccharide contamination. Researchers are encouraged to request the Certificate of Analysis (CoA) for lot-specific data.

Storage, Handling, and Reconstitution

Recombinant proteins require careful handling to maintain activity and integrity. General best practices applicable to HSP90-family recombinant proteins include:

• Storage: Store lyophilized protein at −20 °C or −80 °C. Avoid repeated freeze-thaw cycles.
• Reconstitution: Reconstitute lyophilized preparations in sterile deionized water or the buffer specified in the datasheet. Allow the vial to equilibrate at room temperature before opening.
• Working aliquots: Prepare single-use aliquots after reconstitution and store at −80 °C for long-term use.
• Carrier protein: Addition of 0.1% BSA may improve stability during dilution for some recombinant proteins.

Always refer to the product-specific datasheet supplied with SKU rp373251 for confirmed storage conditions and reconstitution volumes.

Applications and Research Use

Recombinant Human HSP90AA4P Protein may be applicable in a range of research contexts depending on confirmed protein activity, including:

• Biochemical assays: Use as an antigen for antibody validation or as a positive control in Western blot and ELISA experiments.
• Protein–protein interaction studies: Investigate potential interactions between HSP90AA4P-derived sequences and known HSP90 client proteins or co-chaperones.
• Pseudogene research: Explore whether this pseudogene-derived protein retains structural or functional similarity to canonical HSP90 alpha proteins.
• Stress response research: Study its potential role, if any, in cellular responses to heat, oxidative stress, or proteotoxic conditions.

Application suitability should be verified experimentally. Researchers are advised to contact Aladdin Scientific technical support for guidance on specific assay compatibility.

Ordering and Technical Support

Recombinant Human HSP90AA4P Protein is available from Aladdin Scientific under SKU rp373251. To place an order or request a quotation, visit the Aladdin Scientific website or contact your regional sales representative.

For technical questions regarding reconstitution protocols, assay compatibility, or lot-specific quality data, please contact Aladdin Scientific technical support and reference the product SKU and batch number. A Certificate of Analysis (CoA) and Safety Data Sheet (SDS) are available upon request.

For returns, refunds, or shipping inquiries, please refer to Aladdin Scientific's standard policies available on the company website or contact customer service directly.