What Is HSPBAP1 and Why Is It Studied?

HSPBAP1 (Heat Shock Protein 90 Alpha-Associated Protein 1) is a protein that was originally identified as a binding partner of HSP90α, a major molecular chaperone involved in protein folding, stability, and intracellular signaling. HSPBAP1 contains a SANT domain and has been implicated in chromatin remodeling and transcriptional regulation. Research interest in HSPBAP1 has grown due to its potential roles in histone modification pathways and its association with cellular stress responses. The recombinant human form of this protein enables researchers to study its biochemical properties, binding interactions, and functional roles in a controlled in vitro setting.

Expression System, Purity, and Product Specifications

The Recombinant Human HSPBAP1 Protein (SKU: rp374311) supplied by Aladdin Scientific is produced using recombinant expression technology. Specific details regarding the expression host system (e.g., E. coli, insect cells, or mammalian cells), purity grade, molecular weight confirmation by SDS-PAGE, and tag information are available on the product datasheet. Researchers are advised to consult the current product datasheet or contact Aladdin Scientific technical support for the most accurate and up-to-date specifications, as these parameters are critical for experimental design and data interpretation.

Note: Purity, tag identity, and expression host details have not been independently confirmed from the source material provided and are flagged for verification.

Storage, Stability, and Handling Guidelines

Proper storage and handling of recombinant proteins is essential to preserve activity and avoid degradation. As a general guideline for recombinant proteins of this type, users should:

• Store the protein at –20°C or –80°C upon receipt, following the specific temperature recommendation on the product datasheet.
• Avoid repeated freeze-thaw cycles, which can reduce protein integrity. Aliquot the stock into single-use volumes before freezing.
• Keep the protein on ice during experimental setup to minimize activity loss.
• Reconstitute lyophilized material (if applicable) in the recommended buffer as specified in the datasheet, allowing gentle mixing rather than vortexing.
• Confirm storage conditions from the official product datasheet, as formulation and carrier protein content may vary.

For product-specific storage instructions, always refer to the Aladdin Scientific datasheet accompanying SKU rp374311.

Recommended Research Applications

Recombinant Human HSPBAP1 Protein is suitable for a range of in vitro research applications, which may include:

• Protein–protein interaction studies: Investigating binding partners of HSPBAP1, particularly its interaction with HSP90α and other chaperone-associated proteins.
• Biochemical assays: Use as a substrate or control in enzyme activity assays, pull-down assays, and co-immunoprecipitation experiments.
• Structural studies: Supporting structural characterization by techniques such as circular dichroism or size-exclusion chromatography.
• Antibody validation: Serving as a positive control antigen for validating anti-HSPBAP1 antibodies in Western blot or ELISA formats.

Researchers should verify the suitability of the protein for specific assay formats by referring to the product datasheet and any application-specific validation data provided by Aladdin Scientific.

Ordering, Quality Assurance, and Technical Support

Recombinant Human HSPBAP1 Protein (SKU: rp374311) is available for order directly through Aladdin Scientific. Each lot is subject to quality control testing; a Certificate of Analysis (CoA) is available upon request and should be reviewed before use to confirm lot-specific purity and activity data.

For technical questions regarding experimental design, compatibility, or troubleshooting, researchers are encouraged to contact Aladdin Scientific's technical support team. For order inquiries, pricing, and shipping information, please visit the Aladdin Scientific website or contact your regional sales representative. Returns and refunds are handled in accordance with Aladdin Scientific's standard policies — please refer to the company's returns and refund policy page for details.