What Is Recombinant Human INHBC Protein?

Recombinant Human INHBC Protein is a recombinantly expressed form of the Inhibin Subunit Beta C (INHBC), a member of the transforming growth factor-beta (TGF-β) superfamily. INHBC can heterodimerize with other inhibin/activin subunits to form activin C or activin AC complexes, which participate in the regulation of cellular differentiation, proliferation, and homeostasis. The recombinant protein is produced to support in vitro research applications requiring high purity and lot-to-lot consistency.

What Are the Recommended Research Applications?

Recombinant Human INHBC Protein is suitable for a range of in vitro biochemical and cell biology applications. Typical uses include:

• Cell signaling studies: Investigating activin/inhibin signaling cascades, particularly SMAD pathway activation.
• Cell differentiation assays: Evaluating the role of activin C complexes in differentiation of hepatic, gonadal, or other cell types.
• Binding and interaction studies: ELISA-based or surface plasmon resonance (SPR) assays to characterize receptor binding.
• Functional bioassays: Assessing biological activity in reporter gene or proliferation assays.

Researchers should validate optimal concentrations and assay conditions in their specific experimental systems.

How Should Recombinant Human INHBC Protein Be Stored and Handled?

Proper storage and handling are critical to maintaining the activity and integrity of Recombinant Human INHBC Protein. General best-practice guidelines for recombinant proteins of this class include:

• Store lyophilized protein at –20 °C or –80 °C upon receipt, protected from moisture and light.
• Reconstitute in the recommended buffer (typically sterile PBS or manufacturer-specified diluent) at the suggested concentration.
• Aliquot reconstituted protein to avoid repeated freeze-thaw cycles, which can degrade activity.
• Use within the recommended period after reconstitution; store working aliquots at 4 °C for short-term use (generally up to 1 week).

Always refer to the product datasheet for lot-specific storage instructions, reconstitution volumes, and expiry information.

Quality, Purity, and Regulatory Considerations

Recombinant Human INHBC Protein from Aladdin Scientific is intended exclusively for research use and is not approved for therapeutic, diagnostic, or veterinary applications. Quality attributes typically characterized for recombinant proteins in this category include:

• Purity: Assessed by SDS-PAGE and/or HPLC; high-purity lots minimize interference in sensitive assays.
• Biological activity: Verified by functional bioassay where applicable.
• Endotoxin level: Tested to ensure suitability for cell-based assays.
• Identity: Confirmed by N-terminal sequencing or mass spectrometry.

Specific purity values, activity data, and endotoxin levels for each lot are provided in the certificate of analysis (CoA) available upon request.

How to Order Recombinant Human INHBC Protein from Aladdin Scientific

Recombinant Human INHBC Protein is available from Aladdin Scientific under SKU rp368374. To place an order or request additional product information:

• Search for SKU rp368374 directly on the Aladdin Scientific website.
• Contact your regional Aladdin Scientific sales representative or customer service team for bulk pricing, custom formulations, or expedited shipping inquiries.
• Request a Certificate of Analysis (CoA) or Safety Data Sheet (SDS) through the product page or by contacting support.

For procurement teams, Aladdin Scientific supports institutional purchase orders and offers volume discount programs for qualifying orders.