Recombinant Human KXD1 Protein: FAQs & Specs
Recombinant Human KXD1 Protein: FAQs & Specs
Recombinant Human KXD1 Protein is a research-grade recombinant protein derived from the human KXD1 gene, produced for use in biochemical, cell biology, and protein–protein interaction studies.
- Product Name
- Recombinant Human KXD1 Protein
- SKU
- rp375165
- Source
- Human KXD1 gene, recombinant expression
- Application
- Biochemical assays, protein interaction studies, cell biology research
- Storage
- Refer to product datasheet; typically -20°C or -80°C to avoid repeated freeze-thaw cycles
- Purity
- Refer to product datasheet for lot-specific purity data
What Is Recombinant Human KXD1 Protein?
KXD1 (KxDL motif-containing protein 1) is a human protein associated with the biogenesis of lysosome-related organelles complex 1 (BLOC-1). It contains a conserved KxDL motif and plays a role in intracellular vesicle trafficking and organelle biogenesis. Recombinant Human KXD1 Protein (SKU: rp375165) is produced using recombinant DNA technology, enabling researchers to obtain a well-defined, reproducible protein preparation for use in downstream assays. This product is supplied by Aladdin Scientific and is intended strictly for research use, not for diagnostic or therapeutic applications.
Reconstitution and Storage Guidelines
For optimal performance, Recombinant Human KXD1 Protein should be reconstituted according to the instructions provided in the product-specific datasheet. As a general guideline for lyophilized recombinant proteins, sterile deionized water or an appropriate buffer (such as PBS) is commonly used for reconstitution. After reconstitution, the protein should be aliquoted to avoid repeated freeze-thaw cycles, which can lead to activity loss and protein aggregation. Long-term storage is typically recommended at -80°C, while short-term storage (up to 1 month) may be maintained at -20°C. Always refer to the lot-specific datasheet (SKU: rp375165) for precise reconstitution volumes and storage conditions, as these may vary by formulation.
Recommended Applications and Quality Assurance
Recombinant Human KXD1 Protein is suitable for a range of research applications, including but not limited to: in vitro binding assays, co-immunoprecipitation studies, Western blot validation, and structural or functional studies of the BLOC-1 complex. Purity and biological activity data are provided on a lot-specific basis in the product datasheet. Researchers are advised to consult the datasheet for SDS-PAGE purity information, endotoxin levels, and any functional activity test results. If specific functional data are required, contact Aladdin Scientific technical support for the most current lot release data.
Ordering, Shipping, and Returns
Recombinant Human KXD1 Protein (rp375165) can be ordered directly through the Aladdin Scientific website or by contacting your regional sales representative. The product is shipped under conditions appropriate for protein stability, typically with dry ice for frozen formulations. Upon receipt, immediately inspect the package and store the product as directed. For return or refund inquiries related to this product, please review Aladdin Scientific's return and refund policy or contact customer service. Bulk quantities or custom formulations may be available upon request; inquire with the sales team for pricing and lead times.
Frequently Asked Questions Overview
The following FAQ section addresses the most common inquiries from research scientists and lab managers regarding Recombinant Human KXD1 Protein (rp375165). Topics include biological background, technical handling, quality specifications, and procurement logistics. For questions not addressed here, please contact Aladdin Scientific technical support or customer service directly.
Frequently asked questions
What is the biological function of KXD1 and why is it used in research?
KXD1 is a subunit associated with the BLOC-1 complex, which is involved in the biogenesis of lysosome-related organelles and intracellular vesicle trafficking. Researchers use recombinant KXD1 protein to study protein–protein interactions within the BLOC-1 complex, to investigate trafficking pathways, and to understand disease mechanisms linked to organelle biogenesis disorders. Its conserved KxDL motif makes it a useful tool for probing complex assembly and function.
How should I reconstitute and store Recombinant Human KXD1 Protein (rp375165)?
Reconstitution and storage conditions are specified in the lot-specific product datasheet included with the product. In general, lyophilized recombinant proteins are reconstituted with sterile deionized water or PBS to the recommended concentration, then aliquoted and stored at -80°C for long-term use. Avoid repeated freeze-thaw cycles to preserve protein integrity and activity. Always consult the datasheet for the exact recommended conditions for this product.
What purity and quality controls are applied to Recombinant Human KXD1 Protein?
Purity is assessed by SDS-PAGE and the results are reported on the lot-specific certificate of analysis (CoA). Endotoxin levels are typically tested by LAL assay. Specific purity percentages and endotoxin thresholds are provided in the product datasheet for SKU rp375165. For the most current lot release data, contact Aladdin Scientific technical support.
Is Recombinant Human KXD1 Protein (rp375165) suitable for in vivo or clinical use?
No. Recombinant Human KXD1 Protein is supplied for research use only and is not intended for diagnostic, therapeutic, or clinical applications. It has not been evaluated for safety or efficacy in humans or animals for medical purposes. Researchers must comply with all applicable institutional and regulatory requirements when using this reagent.
How can I order Recombinant Human KXD1 Protein, and what is the return policy?
The product (SKU: rp375165) can be ordered via the Aladdin Scientific website or through a regional sales representative. For returns or refunds, please refer to Aladdin Scientific's official return and refund policy available on the website, or contact customer service directly. As a biological reagent, returns may be subject to specific conditions; contacting customer service promptly upon receipt of a damaged or incorrect shipment is strongly recommended.
References
- Starcevic M, Dell'Angelica EC. Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/merlin) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1). J Biol Chem. 2004;279(27):28393-28401. doi:10.1074/jbc.M402929200
- Ghiani CA, Dell'Angelica EC. Dysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade. ASN Neuro. 2011;3(2):e00058. doi:10.1042/AN20110010
- Aladdin Scientific. Recombinant Human KXD1 Protein (rp375165) Product Datasheet. Aladdin Scientific; [cited 2024]. Available from: https://www.aladdin-e.com
Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
危险品化学品经营许可证（带存储）