DNA sequencing is divided into manual sequencing and automated sequencing, and manual sequencing includes the Sanger double deoxy chain termination method and the Maxam-Gilbert chemical degradation method. Automated sequencing has actually become the mainstream of DNA sequence analysis today. PE ABI has produced DNA sequencers such as Model 373, Model 377, Model 310, Model 3700 and Model 3100, of which Model 310 is one of the most used models in clinical testing laboratories.

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