Proteolytic Enzyme Networks in Cell Injury: Activation Sequence, Substrate Cleavage, and Experimental Attribution
The proteolytic enzyme network in cell injury involves calpains, caspases, cathepsins, MMP/ADAM family proteases, and the ubiquitin-proteasome system. Different proteolytic enzymes correspond to Ca²⁺ overload, apoptotic execution, lysosomal injury, extracellular matrix remodeling, and disrupted ...
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