The MCM protein family is a core component of DNA replication licensing and replication origin activation. MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7 jointly form the MCM2-7 complex, which is loaded onto replication origins in G1 phase and forms the CMG helicase with CDC45 and GINS in S phase, ...
RNA-DNA hybrids are nucleic acid structures formed by pairing between an RNA strand and a DNA template strand. Typical forms include transcription-associated R-loops and hybrid regions formed after ribonucleotides are incorporated into DNA. RNase H1, RNase H2, helicases, topoisomerases, and ...
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